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Cholinergic modulation of dopamine-related effects of ethanol in the rat
(2024-04-25)
Alcohol use disorder is associated with serious medical consequences leading to preterm death. Alcohol activates the brain reward system, leading to an increase of extracellular dopamine (DA) levels in the nucleus accumbens ...
Psychological outcomes during rehabilitation after ACL reconstruction - and implications for second ACL injury
(2024-04-24)
An anterior cruciate ligament (ACL) injury is
a common knee joint injury. An ACL injury
is typically managed through surgical
reconstruction of the ligament, followed by
rehabilitation. For patients treated with ...
Predictors of severe kidney disease in long-term lithium treatment
(2024-04-22)
The thesis aims to advance the understanding of severe chronic kidney disease in lithium-treated patients through four observational studies in which subjects were recruited from the Sahlgrenska University Hospital laboratory ...
lnduction Therapies in Multiple Sclerosis - Clinical and immunological follow-up
(2024-03-21)
Multiple sclerosis (MS) is a chronic disease that damages the central nervous system. Its pathophysiology is complex, and consists of inflammation and degeneration from the disease onset. The treatment of MS has continuously ...
Polycystic ovary syndrome in women with severe obesity - effects of a 12-month weight loss intervention
(2024-03-19)
Background: Polycystic ovary syndrome (PCOS) affects one out of eight women and is associated
with reproductive, metabolic, and psychiatric features. There is a strong association with obesity but
studies on PCOS in women ...
Health conditions, functioning and social outcomes in adults with cerebral palsy
(2024-02-21)
Background: A majority of individuals with cerebral palsy (CP) are adults,
and yet healthcare and research are focused on children. In comparison to the
consequences in childhood, little is known about the long-term ...
Regulation of amyloid beta generation and its involvement in synaptic function: studies in human iPSC-derived cortical neurons
(2024-02-21)
Alzheimer’s disease (AD) is a neurodegenerative disease that affects millions of individuals worldwide and exerts a profound societal and economic impact. Clinically characterized by a gradual loss of memory, cognitive and ...
A treatment seeking population with Gambling Disorder - Internet treatment, severity and gender
(2024-02-21)
Gambling is a common pastime all over the world, but can become harmful in excess and can even develop into an addictive behavior, a Gambling Disorder (GD). The aim of this thesis was to contribute to the clinical understanding ...
Outcome after treatment of cerebral aneurysms
(2024-02-08)
single centre follow-up of patients that had been treated at our institute with a flow diverter where we in the follow-up identified three-quarters of the aneurysms treated to have an aneurysm occlusion and that patients >70 years had a lower occlusion...
Speech production and literacy in students with intellectual disabilities and communication difficulties
(2024-02-07)
Many individuals with intellectual disabilities have difficulties with spoken communication and literacy learning leading to vulnerability. It has been suggested that interventions to promote reading in this group not only ...