Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi by Title
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22q11 Deletion Syndrome. Neuropsychological and Neuropsychiatric Correlates. A Clinical Study of 100 Cases
(2007-11-12)Objectives: Examine the prevalence and type of Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity-Disorder (AD/HD), Learning Disability (LD), behavioural profile, intellectual ability/profile, and executive ... -
A Podocyte view on RhoGTPases and actin cytoskeleton regulation
(2020-06-11)Proteinuria is a hallmark symptom of chronic kidney disease, that if left to persist constitutes a risk for progression of disease. Symptomatic treatment aiming at decreasing proteinuria is therefore standard practice. ... -
Acquired epilepsy in Multiple sclerosis: a nationwide register-based investigation into prognosis and treatment
(2022-11-22)The prevalence of epilepsy in persons with multiple sclerosis (MS) is thrice that of the general population. The association between epilepsy and MS prognosis and its management are however largely unknown. The prevalence ... -
Acquired Epilepsy with a Focus on Stroke: Treatment and Prognosis
(2022-02-23)The relationship between epilepsy and stroke is complicated. While stroke is a major cause of epilepsy after middle age, there is also evidence that the risk of stroke is increased in persons with epilepsy. The overall aim ... -
Active Ageing a Path towards Ageing Well. Physical Functioning, Physical Activity, Falls Self-Efficacy and Social Participation in Community-Dwelling Elderly
(2016-01-21)The overall aim of this thesis was to study factors of importance for active ageing with a focus on physical functioning, physical activity, falls self-efficacy, health-related quality of life and social participation in ... -
Acute and chronic effects by stimulants on behavior and striatal neurotransmission in the rat
(2017-08-18)Nicotine and amphetamines are the most widely abused stimulants. The main aim of the studies in this thesis was to investigate how these two drugs of abuse affect distinct regions of the rat brain involved in development ... -
Acute pulmonary embolism - aspects of respiratory symptoms and physical activity
(2022-03-16)Introduction. Pulmonary embolism (PE) is the third most common cardiovascular disease, after myocardial infarction and stroke. Post-PE syndrome, which is characterized by long-term consequences of PE with persistent dyspnea ... -
Adipose tissue mitchondrial function is modulated by antioxidants
(2019-09-23)Antioxidants are widely used as reactive oxygen species (ROS) scavenging agents in experimental research and in conditions where oxidative stress plays a primary role. However, the effect of antioxidant supplementation ... -
ADL assessments after stroke: aspects on reliability. The stability between raters, instruments and modes of administration
(2009-04-14)Activities in daily living, ADL are assessed as an outcome of the rehabilitation process or to be able to determine suitable interventions. The overall aim here was to analyse assessments in terms of ADL in order to ... -
Adult Chiari I malformation - Clinical presentation and surgical outcomes
(2018-04-04)Background Chiari I malformations (CMIs) are hindbrain anomalies that are characterized by cerebellar tonsillar ectopia. The typical presentation is an occipital headache that worsens with exertion. In this thesis, I focus ... -
Adult psychiatric outpatients; neuropsychiatric, neuropsychological and neurodevelopmental aspects
(2024-12-05)ABSTRACT Background: Neurodevelopmental disorders - including autism and attention- deficit/hyperactivity (ADHD) - are relatively common in the general population with a total prevalence rate of at least 10%. Most research ... -
Advanced renal cell carcinoma - The role of orellanine and associated therapeutic challenges
(2018-12-20)Orellanine is a fungal nephrotoxin selectively toxic to the human tubular epithelial cells (HTEC) of the kidney nephrons leading to kidney failure. Patients treated with renal replacement therapy after orellanine poisoning ... -
Affective touch throughout life: from cortical processing in infancy to touch perception in adulthood
(2017-05-09)Affective, interpersonal touch is important for forming and maintaining social bonds. In the hairy skin of humans there is a specific type of nerve fibers called C-tactile (CT) afferents which are optimally activated by a ... -
The AfterBabyBodyStudy: Muscular changes, exercising, and activity limitations and their associations with pelvic girdle pain and urinary incontinence in the postpartum period
(2023-11-21)Aim: Pregnancy and childbirth can lead to several symptoms, changes in the pelvic floor muscles and a diastasis recti abdominis (DRA). This thesis aimed to assess and explore stress urinary incontinence, vaginal heaviness, ... -
Aggressive Antisocial Behavior: Risk Factors and Personality Profile
(2016-11-18)Background: There is an increasing knowledge that violent criminality is restricted to a group of individuals with early onset of behavioral problems. These problems often emerge in combination with substance abuse and ... -
Airway reactions and breathing movements in sensory hyperreactivity
(2013-03-05)Abstract Patients diagnosed with sensory hyperreactivity, SHR, suffer from upper and lower airway symptoms like cough, difficulties to breathe and chest pain, induced by a variety of environmental irritants but also by ... -
Alcohol use among older adults: Population perspectives on prevalence, correlates, and consequences of drinking in Swedish 70-year-olds
(2023-04-25)Background: Alcohol consumption is a major contributor to global morbidity and mortality, as well as accidents and intentional injuries. Older adults may be particularly susceptible to these negative consequences due to ... -
Alzheimer's disease and vascular dementia in population-based studies
(2021-03-30)Dementia, a clinical syndrome with several profiles and causes, is characterised by a decline in cognitive functions, including memory, learning, executive function, attention, language, and social ability. The most common ... -
Alzheimer’s Disease: effect of Tau-related genes on the pathology, neurochemistry and risk of disease
(2007-11-07)Alzheimer’s disease (AD) is the most common form of dementia in the elderly. The predominant sporadic form of AD is a genetically complex disorder probably involving a combination of genetic factors together with environmental ... -
Amyloid Maturation Patterns in Alzheimer's Disease - Novel chemical imaging of Aβ and Tau pathology
(2023-10-11)Alzheimer’s disease (AD) accounts for approximately 70% of dementia cases in Sweden. It can be of genetic origin i.e. familial form (fAD), sporadic form (sAD). AD is characterized by the deposition of amyloid and tau ...