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Regulation of postnatal neurogenesis and brain angiogenesis by thyroid hormone
(2009-12-07)
Thyroid hormone (TH), which is secreted by the thyroid gland, exerts significant
effects on the central nervous system (CNS), especially during development, so
that delayed treatment of perinatal hypothyroidism results ...
Susceptibility genes in conformational diseases
(2009-12-04)
Conformational diseases are characterized by protein misfolding and aggregation in the affected tissue. The aim of this thesis was to find genetic support for mechanisms in common for three prevalent confor-mational diseases: ...
On The Innervation of Salivary Glands and Treatment of Dry Mouth - An Experimental and Clinical Study
(2009-11-19)
Detailed knowledge of the innervation of the parotid gland is essential in basic studies on various neuroglandular phenomena as well as in various types of orofacial surgery. The innervation is more complex than usually ...
On the influence of dopamine-related genetic variation on dopamine-related disorders
(2009-11-13)
Rationale: Dopamine synthesizing neurons are involved in a wide variety of functions. The most prominent dopamine pathways originate in the midbrain. The development, function and survival of these dopaminergic neurons are ...
A pathway for pleasant touch: linking peripheral receptors to central processing and hedonic experience
(2009-11-10)
This thesis investigates the mechanisms underpinning pleasant touch, describes a pathway from peripheral nerve endings in the skin to the insular cortex, and relates these findings to the subjective hedonic experience of ...
Machine learning for identification of brain activity patterns with applications in gentle touch processing
(2009-10-23)
activity, acquired using functional magnetic resonance imaging (fMRI), is a prime example of such complex data where the utility of pattern recognition has been demonstrated in a wide range of studies recently (Haynes et al., Nature Reviews Neuroscience...
Secretory and anti-inflammatory actions of some gastro-intestinal hormones in salivary glands
(2009-09-17)
Textbooks generally state that the secretory activity of salivary glands is solely regulated by nerves. This view is challenged in the present Thesis, using the parotid gland of the anaesthetized rat as experimental in ...
Targeted Abeta proteomics - A tool to study the pathogenesis of Alzheimer's disease
(2009-09-04)
Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder of the central nervous system. Diagnosis and monitoring of sporadic AD has long depended on clinical examination of individuals with end-stage ...
Inflammation and behavior following irradiation-induced injury in the developing brain
(2009-08-28)
Radiotherapy is used in the treatment of pediatric brain tumors and is often associated with debilitating late effects, such as intellectual impairment. Areas in the brain harboring stem cells are particularly sensitive ...
Gastric Inhibitory Polypeptide in the brain
(2009-06-30)
The hippocampus is an area of active cell proliferation and neurogenesis within the adult
mammalian brain. Adult neurogenesis is of great importance for the brain, since it increases
neuroplasticity and the ability to ...