Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 354-373 of 636
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Narcolepsy in children: Relationship to the H1N1 influenza vaccination, association with psychiatric and cognitive impairments and consequences in daily life
(2016-09-06)Background/aims: Narcolepsy is a lifelong sleep disorder with an onset most frequently in the second decade of life. The cardinal symptoms are excessive daytime sleepiness, cataplexy, hypnagogic and hypnopompic hallucinations ... -
Nasopharyngeal carcinoma: past, present and future directions
(2007-12-07)Nasopharyngeal carcinoma (NPC) is a rare disease in Sweden. The purpose of this thesis was to investigate the clinicopathological manifestations of the disease and its treatment outcomes in a cohort of Swedish NPC patients ... -
Necrotizing enterocolitis - growth, bone health and intestinal microbiota during childhood
(2023-05-24)Necrotizing enterocolitis (NEC) is a dreaded gastrointestinal disease primarily affecting infants born preterm. Despite extensive research, NEC is still one of the most devastating diseases in neonatal intensive care. ... -
Neonatal invasive infections with focus on Group B streptococci
(2021-08-18)Invasive infections affect neonates with the risk of severe morbidity and death, and Streptococcus agalactiae (Group B streptococcus, GBS) remains one of the most common pathogens. The aim of this thesis was to assess ... -
Neurochemical and cognitive aftermaths of surgery - studies on short- and long-term effects of surgery and anesthesia
(2020-10-01)Background: Each year, around the world, more than 230 million patients have surgery. Improvements in healthcare have resulted in older and sicker patients undergoing surgical interventions. As a result, surgical safety ... -
Neurochemical and neuroendocrine reactions during non-neurological surgery
(2010-01-14)Abstract Objective: To study changes in serum and cerebrospinal fluid (CSF) proteins, monoamine metabolites and hormones during non-neurological surgery. Subjects and methods: Thirty-five patients without neurological or ... -
Neurogenic bladder and bowel dysfunction - incontinence and life situation in adolescents and adults with spina bifida
(2021-01-07)Neurogenic bladder and bowel dysfunction - incontinence and life situation in adolescents and adults with spina bifida Magdalena Vu Minh Arnell Department of Pediatrics, Institute of Clinical Sciences Sahlgrenska ... -
Neuroinflammation and pain
(2014-09-05)ABSTRACT Background: Persistent pain that remains long after the physiological trigger has been resolved is a disabling condition. A possible mechanism for the transition from acute physiological pain to persistent pain ... -
Neuropsychological outcomes and health-related quality of life of children operated for nonsyndromic craniosynostosis
(2021-04-06)The primary aim of this thesis was to assess the intelligence quotient, attention function, adaptive behavior skills, and health-related quality of life of children operated for nonsyndromic craniosynostosis. The secondary ... -
New perspectives on imaging of urinary tract infections in infants
(2020-10-20)Background: Urinary tract infection (UTI) is a common disease in infants that may lead to renal damage with an increased risk of long term complications. The diagnostic imaging aims to identify risk factors as underlying ... -
New Prognostic Markers in Stage III Serous Ovarian Adenocarcinomas
(2008-05-15)Ovarian carcinoma is the fifth most common cause of cancer death in Swedish women. Patients with advanced-stage disease respond differently to treatment, and the clinical outcome is difficult to predict for an individual ... -
Nitric oxide donors in labor management
(2007-06-08)ABSTRACT Nitric oxide donors in labor management Maria Bullarbo Department of Obstetrics and Gynecology Institute of Clinical Sciences Background: Nitric oxide (NO), a free radical with ultra-short ... -
Non-attendees need attention - Determinants and interventions affecting participation in cervical cancer screening
(2014-09-19)Aim: Non-attendance is the foremost screening-related risk factor for cervical cancer. The overall aim of this thesis is to contribute to preventing cervical cancer by focusing attention on non-attendees, assessing ... -
Nonsynostotic plagiocephaly: Prevention strategies in child health care
(2019-04-18)The aim of this project was to assess whether it is possible to prevent nonsynostotic plagiocephaly while still promoting safe infant sleeping practices. A continuing education including guidelines was developed for child ... -
Novel biomarkers associated with histotype and clinical outcome in early-stage ovarian carcinoma
(2020-04-15)Ovarian cancer is a collective name for multiple malignancies deriving from or involving the ovary, mainly comprising five histotypes of epithelial origin (clear-cell (CCC), endometrioid (EC), high-grade serous (HGSC), ... -
Novel biomarkers prediciting long-term survival in breast cancer.
(2009-05-15)Breast cancer is the most common malignancy among women, affecting over a million women worldwide every year. During the last decades, there has been a dramatic increase in the survival rates due to earlier detection and ... -
Novel immunotherapies for metastatic melanoma - from mouse models towards clinical trials
(2019-12-06)Immunotherapies including checkpoint blockade and adoptive T cell transfer (ACT) show great promise for the treatment of melanoma, with long-term effects in some patients. However, around half of the patients with metastatic ... -
Novel immunotherapies for metastatic uveal melanoma - From bench to clinical biomarkers
(2022-11-25)Immunotherapy has revolutionized cancer treatment, with durable long-term effects in a proportion of patients. However, in around half of these patients, there are little to no effects. Patients with metastatic uveal ... -
Nutritional aspects of advanced Head and Neck Cancer and impact of different factors in Head and Neck Cancer of Unknown Primary
(2018-05-25)Background/Aims: Swallowing problems and malnutrition are common in advanced head and neck (HN) cancer. The aim of paper I was to study whether percutaneous endoscopic gastrostomy (PEG) affected the long-term swallowing ... -
Obesity and Common Surgical Disorders, Effects on Incidence and Complications
(2011-04-14)Background: Overweight and obesity are becoming increasingly common, not only in the developed countries but also in developing countries. It is well documented that obesity increases the risk of several medical disorders; ...