• Obesity and IVF outcome. The hope of improvements through weight reduction 

  Kluge, Linda (2023-09-20)

  Background: Female obesity is associated with decreased live birth rate (LBR) after in vitro fertilization (IVF) and adverse maternal and perinatal outcomes are increased in obese women compared to normal weight women after ...

• Short- and long-term outcomes after aneurysmal subarachnoid hemorrhage 

  Bjerkne Wenneberg, Sandra (2023-09-15)

  Aneurysmal subarachnoid hemorrhage (aSAH) is a sudden and devastating event with significant morbidity and mortality. The development of delayed cerebral ischemia (DCI) is a major contributor to the observed high morbidity. ...

• Left ventricular dysfunction in critically ill patients 

  Cavefors, Oscar (2023-09-08)

  ABSTRACT Background: Cardiac dysfunction is common in Intensive Care Unit (ICU) patients and can contribute to multiorgan failure and death. Despite this, few studies have been performed on pathogenies, prevalence, ...

• How does the technical status of medical ultrasound equipment affect image quality? Studies based on human observer experiments and a novel method for automatic detection of defective transducers 

  Lorentsson, Robert (2023-08-25)

  Ultrasound as an imaging modality has a fundamental role in modern healthcare. The equipment, especially transducers, is fragile and handled daily, and transducers are known to sometimes become defective. The overall ...

• Checkpoint inhibitor-induced adverse events in the CNS - T-cell characteristics and biomarkers 

  Bjursten, Sara (2023-08-21)

  Immune checkpoint inhibitors (ICI) activate T cells to kill cancer cells by blocking inhibitory receptors PD-1 (nivolumab; nivo) or CTLA-4 (ipilimumab; ipi). Activated T cells can also attack any healthy organ, causing ...

• Bone health and nutrition treatment. Studies on young women with anorexia nervosa and children with epilepsy 

  Svedlund, Anna (2023-08-17)

  Background: Adequate nutritional status is crucial for optimal longitudinal growth and accrual of bone mass during childhood and adolescence. Peak bone mass achieved in young adulthood affects bone health throughout life. ...

• Degenerative cervical myelopathy: Surgical treatment, imaging evaluation, and outcome 

  de Dios Perez, Eddie (2023-08-16)

  Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord impairment in adults worldwide. The overall aims of this thesis were to compare patient-reported clinical outcomes, adverse events, and ...

• Early detection of critical congenital heart defects in Sweden - with a focus on coarctation of the aorta 

  Lannering, Katarina (2023-05-30)

  Introduction: Despite the implementation of prenatal and neonatal screening, newborn infants with critical congenital heart defects (CCHD) remain at risk of being discharged undiagnosed, particularly newborns with coarcation ...

• Distal femur fracture in the elderly patient 

  Paulsson, Martin (2023-05-25)

  Studies on the epidemiology of distal femur fractures show a vast increase in low-energy trauma-associated fractures in older ages. Age-related changes in bones lead to loss of bone matrix and increased porosity, which ...

• Treatment of Head and Neck Cancer, Effects on Health-Related Quality of Life and Nutrition 

  Berg, Malin (2023-05-24)

  The aim of this thesis was to explore the impact of treatment on health-related quality of life (HRQoL), fatigue and nutrition in head and neck cancer (HNC) patients. The tumour locations often induce problems with swallowing ...

• Necrotizing enterocolitis - growth, bone health and intestinal microbiota during childhood 

  Magnusson, Amanda (2023-05-24)

  Necrotizing enterocolitis (NEC) is a dreaded gastrointestinal disease primarily affecting infants born preterm. Despite extensive research, NEC is still one of the most devastating diseases in neonatal intensive care. ...

• On the diagnosis and treatment of intraepidermal carcinoma 

  Fougelberg, Julia (2023-05-24)

  Abstract: Intraepidermal carcinoma (IEC), also known as Bowen disease (BD) or squamous cell carcinoma (SCC) in situ, is a precursor to SCC. The incidence of IEC is increasing rapidly in fair-skinned populations with a ...

• The proteasome as a target for cancer therapy 

  Larsson, Peter (2023-05-23)

  The main objective of this PhD thesis was to evaluate the significance of proteasome genes as prognostic markers for different cancer types and identify specific cancer forms that respond to proteasome inhibition. The ...

• Small-scale dosimetry methods for normal tissues after radioembolization and peptide receptor radiotherapies; a focus on the liver parenchyma and the bone marrow 

  Hemmingsson, Jens (2023-05-23)

  Radionuclide therapies are increasingly used in cancer treatments as they have been proven to be both effective and safe. As biodistributions and uptake vary widely between patients, a standardized approach is bound to ...

• Multimodal and multiscale characterization of bone and bone interfaces in health and disease 

  Micheletti, Chiara (2023-05-16)

  Seeing is believing. Our understanding of phenomena often involves their direct observation. However, bone architecture is challenging to visualize given its multi-level hierarchical organization. In this thesis, bone and ...

• On massive weight loss and body contour 

  Ockell, Jonas (2023-05-16)

  Abstract Background/Aims: Bariatric surgery is an effective treatment for severe obesity. However, massive weight loss is associated with adverse effects, such as excess skin. The overall aim of this thesis was to investigate ...

• Bowel Habits and Functional Constipation - A Longitudinal Birth Cohort Study of Children Born in Gothenburg 

  Gatzinsky, Cathrine (2023-05-15)

  Background: Parents often visit health facilities with concerns regarding their child’s bowel function. Data on bowel habits from healthy children is important in establishing what is normal and what is not. Functional ...

• Childhood asthma. Epidemiology, prevalence and risk factors 

  Strömberg Celind, Frida (2023-05-09)

  Background and aim: Asthma is one of the most common chronic diseases among children often resulting in medical treatment, morbidity and reduced quality of life. It is therefore important to study factors associated with ...

• Rhinosinusitis beyond the upper airways. Epidemiological aspects. 

  Bergqvist, Joel (2023-05-09)

  Rhinosinusitis (RS) is a prevalent, multi-factorial disease, including several subgroups of disease with different characteristics and pathophysiology. RS symptoms for more than 12 weeks are defined as chronic rhinosinusitis ...

• Long-term follow-up after intensive care: Development of an ICU-specific questionnaire 

  Malmgren, Johan (2023-05-03)

  Background: With improved results in intensive care comes a shift in focus – from survival to survivorship. Studies show that ICU survivorship includes effects on, for example, mental and physical health, cognition, ADL, ...

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