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Registry-based studies of return to work after stroke - part of the work after stroke study (WASS)
(2021-02-15)
Objectives. Stroke is one of the most common diseases and a main cause of disability both globally and in Sweden. Even though the risk increases with older age, stroke in the younger population is increasing and a substantial ...
Atrial fibrillation in aging; methodological aspects and the relation to dementia and cerebral vascular disease
(2022-01-12)
Emerging evidence suggest an increased risk of dementia in individuals with atrial fibrillation (AF). However, until recently, few studies have investigated the relation between AF and dementia taking both prevalent and ...
Comprehending the Comprehensive Geriatric Assessment. Feasibility, outcomes and experiences of frail older people
(2020-06-04)
ABSTRACT
Despite existing knowledge on how to approach frail people in health care, the care they receive is commonly not designed to meet their complex needs and support them in maintaining their activities of daily ...
The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury
(2022-01-13)
The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common ...
Virtual reality based kinematics for assessment of post-stroke upper limb function
(2020-04-28)
The main scope of this thesis was to develop a method for assessing the upper limb sensorimotor function following stroke using virtual reality-based technique. The studies reported in this thesis included 67 individuals ...
Revealing the complex nature of amyloid beta and its relation to dementia
(2020-10-20)
Alzheimer disease (AD) is the most common type of dementia and characterized by the accumulation of amyloid plaques in the extracellular space of the brain parenchyma. Amyloid plaques consist of amyloid beta peptides (Aβ). ...
Acquired Epilepsy with a Focus on Stroke: Treatment and Prognosis
(2022-02-23)
The relationship between epilepsy and stroke is complicated. While stroke is a major cause of epilepsy after middle age, there is also evidence that the risk of stroke is increased in persons with epilepsy. The overall aim ...
Appetite-regulating peptides and natural rewards: emphasis on ghrelin and glucagon-like peptide-1
(2020-09-02)
Evolutionary conserved natural behaviors, such as foraging and sexual
behaviors, are strongly associated with reward processes. Brain areas
important for reward processes include, but are not limited to, the nucleus
accumbens ...
Physiological roles of amyloid precursor protein in vivo - zebrafish as a model
(2021-10-26)
Amyloid-beta precursor protein (APP) is an evolutionarily conserved transmembrane protein expressed in many different tissues. APP belongs to a gene family consisting of two other APP-like proteins (APLP1 and APLP2). APP ...
Blood Vessels, Biomarkers, and Broken Barriers: lnvestigations of the Brain Vasculature in Models of Neonatal Brain lnjuries
(2022-02-10)
Brain injury during the perinatal period can lead to lifelong impairment in cognitive and motor function, or an early death. Term neonatal encephalopathy and preterm germinal matrix haemorrhage are two conditions that can ...