Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 457-476 of 636
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Primordial radionuclides in pit lakes in Sweden
(2020-05-07)In Sweden, there are many pit lakes, originating from limestone quarries and metal mines, with unknown status in regard to the activity concentration of radionuclides. Such knowledge is generally available only for pit ... -
Principles of scaffold generation for bioengineering of the ovary and uterus: a study focusing on decellularization
(2021-05-27)Introduction: Cancer therapy often result in fertility problems due to inflicted injury to the reproductive organs. Since most women survive cancer, fertility preservation has become an important consideration during cancer ... -
Prognostic and predictive factors in colorectal cancer
(2009-02-06)Aim: The aim of the thesis was to study prognostic and predictive factors in patients treated for colorectal cancer (CRC). Method: In paper I, a retrospective comparison was made between the patients treated in 1999 ... -
Prognostic factors and tumor treatments in hepatocellular cancer
(2019-03-04)Background: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death worldwide. Prognosis is related to tumor burden, liver function, and performance status as well as treatment factors. ... -
Prognostic impact of coronary microvascular funtion in patients with ischemic heart disease.
(2018-03-09)Background: Ischemic heart disease is the leading cause of death globally. Despite recent advances in interventional and medical therapies, survivors of myocardial infarction are at high risk of recurrent cardiovascular ... -
Promoting the Clinical Relevance of 3D Bioprinting
(2022-02-03)This thesis focuses on the development of methodologies enabling the reconstruction of autologous, functional, and long-term-stable cartilage-like tissue using 3D bioprinting technology and animal experiments. The stability, ... -
Prostaglandins and angiogenesis in experimental cancer
(2010-04-08)Background and aim. Genes, proteins and pathways have been identified and suggested as potential targets in tumor angiogenesis, but current anti-angiogenic therapies have provided only modest benefits in survival of cancer ... -
Prostanoids and colorectal cancer
(2010-10-22)Tumor disease is a main cause of death in Western countries and a most common malignancy is colorectal cancer (CRC). Growing tumors are dependent on interactions among several different cells as well as signaling pathways. ... -
Prostate Cancer and Its Influence on Men´s Daily Lives
(2009-09-30)Prostate cancer has been a disease of older men but age at diagnosis is falling in Sweden. Fatigue has been regarded as a common symptom of cancer and may compromise quality of life in prostate cancer patients. The overall ... -
Prostate Cancer Screening - Aspects of Overdiagnosis
(2014-11-28)The overall aim of this thesis is to explore aspects of overdiagnosis, i.e. the diagnosis of a tumor that in the absence of screening would never have been diagnosed, in prostate cancer (PC) screening. The four papers in ... -
Prostate cancer screening with PSA - A study of potential negative consequences
(2010-11-19)Aims: The Göteborg randomized population-based prostate cancer screening trial is a prospective study evaluating the efficacy of prostate-specific antigen (PSA)-based screening and its effect on prostate cancer mortality. ... -
Prostate Cancer Screening: Outcomes and Risk Prediction
(2018-12-12)Prostate Cancer Screening: Outcomes and Risk Prediction Maria Frånlund, MD Department of Urology, Institute of Clinical Sciences Sahlgrenska Academy at University of Gothenburg, Sweden ABSTRACT The Göteborg Randomized ... -
Prostate Diseases and the Metabolic Syndrome
(2015-04-23)ABSTRACT The overall aim of this thesis was to explore the association between the components of the metabolic syndrome (MetS), including vitamin D, and lower urinary tract symptoms (LUTS). The focus was on the relationship ... -
The proteasome as a target for cancer therapy
(2023-05-23)The main objective of this PhD thesis was to evaluate the significance of proteasome genes as prognostic markers for different cancer types and identify specific cancer forms that respond to proteasome inhibition. The ... -
Proximal and distal humeral fractures. Outcome of primary arthroplasty
(2022-05-19)This thesis deals with both proximal humeral fractures and elbow injuries, especially distal humeral fractures. The main focus is difficult fractures in the elderly. Few randomized controlled trials (RCTs) are available. ... -
Psychosocial Aspects of Dravet Syndrome
(2024-01-15)Dravet syndrome (DS) is a developmental and epileptic encephalopathy, associated with significant neurodevelopmental comorbidity. The aims of this population-based study were to describe the epidemiology, genetics, mortality, ... -
Psychosocial support needs after a breast cancer diagnosis
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Public Health Aspects of Preterm Birth. Studies using Scandinavian population-based data
(2008-05-15)Background: Preterm birth is an unresolved serious global health problem. Research must be multi-disciplinary, with assessment of risk factors and causative agents at many levels of observation. Such an important level is ... -
Pulmonary atresia with intact ventricular septum epidemiology and outcome in children born in Sweden 1980-1999
(2008-04-22)Aims: To describe children born with pulmonary atresia with intact ventricular septum (PA-IVS) in Sweden between 1980 and 1999, the incidence and outcome of PA-IVS, to examine cardio-pulmonary outcomes in survivors and to ... -
Pulmonary ventilation and perfusion assessed by electrical impedance tomography - Experimental studies in pigs
(2009-08-28)Pulmonary ventilation and perfusion and ventilation/perfusion (V/Q) matching determine gas exchange in every lung unit in the healthy state and in the pathologically altered lung. Mismatch of V and Q lead to hypoxaemia and ...