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Prognostic and predictive factors in colorectal cancer


Please use this identifier to cite or link to this item: http://hdl.handle.net/2077/19365

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Title: Prognostic and predictive factors in colorectal cancer
Authors: Derwinger, Kristoffer
E-mail: kristoffer.derwinger@vgregion.se
Issue Date: 6-Feb-2009
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Clincial Sciences. Department of Surgery
Parts of work: I: Kristoffer Derwinger, Göran Carlsson, Bengt Gustavsson. Stage migration in colorectal cancer related to improved lymph node assessment. European Journal of Surgical Oncology 33 (2007) 849-853.
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II: Kristoffer Derwinger, Göran Carlsson, Bengt Gustavsson. A study of lymph node ratio as a prognostic marker in colon cancer. European Journal of Surgical Oncology 34 (2008) 771-775.
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III: Kristoffer Derwinger, Yvonne Wettergren, Elisabeth Odin, Göran Carlsson, Bengt Gustavsson. A study of the MTHFR gene polymorphism C677T in colorectal cancer. Accepted Clinical Colorectal Cancer, in press.

IV: Irina Corin, Kristoffer Derwinger, Lisa Larsson, Jörgen Bergström, Bengt Gustavsson. A study of the expression of Cyclin E and its isoforms in tumour and adjacent mucosa, correlated to patient outcome in early colon cancer. Submitted British Journal of Cancer
Date of Defence: 2009-02-26
Disputation: Torsdagen den 26 februari 2009, kl 09.00, Stora aulan, centralkliniken, Östra sjukhuset
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: colorectal cancer
prognosis
lymph nodes
lymph node ratio
MTHFR
cyclin E
TNM
staging
metastasis
Abstract: Aim: The aim of the thesis was to study prognostic and predictive factors in patients treated for colorectal cancer (CRC). Method: In paper I, a retrospective comparison was made between the patients treated in 1999 (n=180) with those treated in 2004 (n=175). During the period, a multidisciplinary team conference and an improved cooperation with the pathologists had been initiated. The focus of interest was the lymph node assessment, its’ development and how this affected clinical staging an... more
ISBN: 978-91-628-7676-0
URI: http://hdl.handle.net/2077/19365
Appears in Collections:Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses from Sahlgrenska Academy

 

 

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