Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 402-421 of 636
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On the pathogenesis of infections associated with percutaneous osseointegrated orthopaedic implants
(2018-11-22)Orthopaedic implants enable the restitution of locomotor function and improve the quality of life of many people. However, biomaterial-associated infection may occur due to the propensity of microorganisms to adhere and ... -
On the role of surface properties for implant fixation : From finite element modeling to in vivo studies
(2015-05-13)The aim of this thesis was to gain a deeper understanding of the factors contributing to the fixation of bone-anchored implants, especially with regard to surface chemistry, surface topography and implant loading. The ... -
On the treatment of tibial fractures using the Ilizarov fixator
(2014-08-29)The aim of this thesis was to analyse the results of the Ilizarov method in patients with different types of tibial fracture and compare them with conventional methods, in terms of primary union, complication rates, ... -
On tissue engineering of pig, human, and non-human primate tissues
(2020-05-07)Background: Demand for donor organs for transplantation has been increasing every year more than the actual supply of suitable donor organs. One of the major problems associated with allogeneic transplantation includes ... -
On tissue reactions to dentin as a bone substitute material
(2017-08-15)Background Reconstruction of the jaws due to resorption of the alveolar crest may require bone augmentation prior to installation of endosseous implants. Active research on new bone graft materials with bone regeneration ... -
On various protocols for direct loading of implant-supported fixed prostheses
(2007-11-30)Backgrund: Prosthetic rehabilitation of the edentulous patient with implant-supported bridges is today a routine and predictable treatment modality. The original protocol prescribed a healing period of 3 to 6 months prior ... -
Open and closed endotracheal suctioning. Experimental and human studies.
(2007-04-20)Background: The practice of endotracheal suctioning of ventilator treated patients is necessary to remove secretions to prevent obstruction of the endotracheal-tracheal tube and lower airways. This very common procedure ... -
Opportunistic viral infection after paediatric transplantation
(2009-04-17)Background: Opportunistic viral infections can cause considerable morbidity and mortality in organ and stem cell transplanted (SCT) patients, mainly due to iatrogenic T cell dysfunction. Whereas in SCT patients, in general ... -
Optimisation of radionuclide therapy by reduction of normal tissue damage
(2022-05-10)Background:177Lu-octreotate is used to treat patients with neuroendocrine tumours (NETs) often resulting in prolonged life and better quality of life, but is today seldom a cure for these patients. Optimisation of ... -
Optimization of image acquisition parameters in chest tomosynthesis - Experimental studies on pulmonary nodule assessment and perceived image quality
(2016-12-14)Chest tomosynthesis refers to the technique of acquiring a number of discrete projection images within a limited angular range around the patient. These projection images are then used to reconstruct section images of the ... -
Optimization of paediatric CT examinations - An approach to minimize absorbed dose to patients with regard to image quality and observer variability
(2011-02-25)The absorbed dose to paediatric patients is important bearing in mind the increased risk of radiation-induced cancer due to exposure to X-rays at young ages. Questions have also been raised of whether a CT examination of ... -
Optimization of radiotherapy in locally advanced lung cancer
(2011-12-20)Lung cancer is the leading cause of cancer death worldwide as well as in Sweden, where the incidence is around 3500 new cases per year. About 50% have distant metastases by the time of diagnosis and are treated with ... -
Optimized use of MRI in a PSA based prostate cancer screening program
(2021-05-07)The overall aim of this thesis was to optimize different aspects of the use of MRI in screening for prostate cancer. Paper 1 was based on preoperative MRI in a prostatectomy cohort. Papers 2-4 were based on data from the ... -
Optimizing postoperative radiation therapy in prostate cancer: focus on side-effects, practical implementation and dose distribution
(2020-08-18)Optimizing postoperative radiotherapy in prostate cancer: focus on side effects, practical implementation and dose distribution Karin Braide, MD Department of Urology, Institute of Clincal Sciences Sahlgrenska Academy, ... -
Optimizing the early diagnosis process of urinary bladder cancer. On standardized care pathway, computed tomography, artificial intelligence, and a newly developed urine-based cancer marker
(2024-04-25)The thesis contains of five articles in three different subprojects. The overall aim of this thesis is to investigate the development of the investigation of macroscopic hematuria over time, the effects of this development ... -
Orbital floor fractures - aspects of diagnostic methods, treatment and sequelae
(2006-06-08)Despite surgical intervention, orbital floor fractures are associated with risks of persisting sensibility disturbances, enophthalmos and diplopia. Cheek asymmetry and trismus may result when the zygoma is dislocated. In ... -
Orthogeriatric anaesthesia - studies on the bone cement implantation syndrome, risk prediction and intraoperative haemodynamics
(2021-05-17)The bone cementation implantation syndrome (BCIS), as seen in orthopaedic patients, is characterised by intraoperative hypotension and hypoxia and loss of consciousness around the time of bone cementation. In a retrospective ... -
Osteocytes as indicators of bone quality - multiscale structure-composition characterisation of the bone-implant interface
(2017-09-01)By virtue of certain design features, bone anchored metal implants can be made to elicit a strong initial osteogenic response, i.e., the amount of bone formed. While quantitative differences are often lost at longer follow ... -
Otosclerosis; clinical long term-perspectives
(2013-04-03)This thesis has assessed medical, technical and health-related aspects of otosclerosis from a long-term perspective. A retrospective clinical study was performed where 65 subjects who had previously undergone stapedectomy ... -
Outcome Measures of Functioning and Physical Activity in Patients with Low Back Pain - Exemplified in Patients Who Undergo Lumbar Fusion Surgery
(2019-01-09)INTRODUCTION: Chronic low back pain (LBP) can negatively affect health in terms of disability and decreased levels of functioning and physical activity. Chronic LBP due to degenerative disc disease (DDD) is a subgroup ...