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Opportunistic viral infection after paediatric transplantation


Please use this identifier to cite or link to this item: http://hdl.handle.net/2077/19392

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Title: Opportunistic viral infection after paediatric transplantation
Authors: Kullberg-Lindh, Carola
E-mail: carola.kullberg-lindh@pediat.gu.se
Issue Date: 17-Apr-2009
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Clincial Sciences. Department of Pediatrics
Parts of work: I. Kullberg-Lindh C, Ascher H, Krantz M, Lindh M. Quantitative analysis of CMV DNA in children the first year after liver transplantation. Pediatr Transplant 2003;7: 296-301.
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II. Kullberg-Lindh C, Ascher H, Saalman R, Olausson M, Lindh M. Epstein-Barr viremia levels after pediatric liver transplantation as measured by real-time polymerase chain reaction. Pediatr Transplant 2006;10(1):83-89.
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III. Kullberg-Lindh C, Olofsson S, Brune M, Lindh M. Comparison of serum and whole blood levels of cytomegalovirus and Epstein-Barr virus DNA. Transplant Infect Dis 2008; 10; 308-315.
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IV. Kullberg-Lindh C, Mellgren K, Friman V, Ascher H, Lindh M. Opportunistic viral infections after paediatric stem cell transplantation. Submitted.
Date of Defence: 2009-05-08
Disputation: Fredagen den 8 maj 2009, kl. 13.00, Föreläsningssal 1, Drottning Silvias Barn- och ungdomssjukhus, SU/Östra
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: Paediatric liver transplantation
paediatric stem cell transplantation
immunosuppression
opportunistic
CMV
EBV
AdV
HHV-6
real-time PCR
monitoring
specimen
post transplant lymphoproliferative disease
Abstract: Background: Opportunistic viral infections can cause considerable morbidity and mortality in organ and stem cell transplanted (SCT) patients, mainly due to iatrogenic T cell dysfunction. Whereas in SCT patients, in general the immunosuppressive treatment can be discontinued after 6-12 months, for the majority of organ transplanted patients, the need for treatment is life-long. Aims: This thesis focuses on infections with cytomegalovirus (CMV), Epstein-Barr virus (EBV), adenovirus (AdV) and hum... more
ISBN: 978-91-628-7759-0
URI: http://hdl.handle.net/2077/19392
Appears in Collections:Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses from Sahlgrenska Academy

 

 

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