Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Title
Now showing items 225-244 of 609
-
Food allergy in adults
(2015-04-08)The knowledge on adverse reactions to foods and the spectrum of food-related gastrointestinal symptoms in relation to allergy in adults is still scarce. The conventional allergy tests do not always offer with precision ... -
Food-related gastrointestinal symptoms, nutrient intake and dietary interventions in patients with irritable bowel syndrome
(2015-01-09)Food is a recurrent problem in irritable bowel syndrome (IBS) and it is common to exclude foods, which could lead to a reduced nutrient intake. Perceived food intolerance is very common in IBS, but if specific or more ... -
Frail elders´experiences of health: A combination of qualitative and quantitative studies with a salutogenic perspective
(2014-05-23)Abstract The overall aim of the thesis was to explore experiences of health and its´ influencing factors among frail elders and to evaluate the effect of the intervention Continuum of care for frail elderly people, from ... -
Free Fatty Acid Receptor 2 - A G protein coupled receptor with unique signaling properties in neutrophils
(2022-08-15)The overall aim of the PhD thesis was to determine the role of neutrophil pattern recognition receptors in the initiation and resolution of inflammatory processes. Neutrophil pattern recognition receptors such as the formyl ... -
From efficacy to effectiveness: Two randomized controlled trials of lifestyle intervention postpartum
(2016-11-07)The overall aim of this thesis was to evaluate if, and how, weight loss can be achieved in women with overweight and obesity after pregnancy by combining results from two randomized controlled trials; LEVA and LEVA in Real ... -
Function of Surface-Associated Protein and DNA on Extracellular Vesicles
(2018-05-09)Extracellular vesicles (EVs), including exosomes, are nano-sized, lipid bilayer enclosed vesicles that are released into the extracellular environment from by almost all cells. EVs contain biomolecules, such as proteins, ... -
Functional dualism of antimicrobial host defence peptides
(2009-01-26)Antimicrobial host defence peptides are central to innate immunity and many possess direct antimicrobial actions on bacteria as well as indirect immunomodulatory functions on human leukocytes. Different variants of the ... -
Functional Modulation of the Pattern Recognition Formyl Peptide Receptors in Neutrophils - Lipopeptides - allosteric modulators of G-protein coupled receptors
(2017-01-20)G-protein-coupled receptors (GPCRs), which are the largest class of cell-surface receptors, are involved in a range of physiologic processes and pathologies, making this a highly interesting group of proteins as targets ... -
Gastric electrical stimulation. Studies in patients with intractable nausea and vomiting
(2010-03-02)The most severe cases of gastroparesis are refractory to drugs. In the 1990s gastric electrical stimulation (GES) was introduced for treatment of nausea and vomiting in patients with diabetic and idiopathic gastroparesis. ... -
Gastrointestinal Symtoms and Fatigue in Patients with Quiescent Ulcerative Colitis
(2016-11-10)Gastrointestinal symptoms compatible with Irritable Bowel Syndrome (IBS) and fatigue are common in patients with quiescent ulcerative colitis (UC). The causes of these symptoms remain to be clarified. The overall aim of ... -
General Beliefs about Medicines among Pharmacy Clients, Healthcare Students and Professionals - Group Differences and Association with Adherence
(2008-05-23)Background: only about 50% of all medicines are used as the prescriber intended. If medicines are prescribed in an adequate way, an optimised adherence can decrease mortality and hospitalisation and improve health-related ... -
Genes, lifestyle and coronary heart disease risk-epidemiological interaction studies
(2015-03-03)Coronary heart disease (CHD) has multifactorial background involving both genetic and lifestyle factors, but much is still unknown about their interactions. The aim of this thesis was to study interactions focusing on ... -
Genital tract CD4+ T cells for vaccination and protection against Chlamydia trachomatis
(2009-10-19)Vaccination strategies for protection against sexually transmitted diseases (STDs) are lacking due to an incomplete understanding of genital tract T cell responses. This thesis dissects the generation of T helper subsets, ... -
The GH-IGF-1 Axis in Postmenopausal Women with Abdominal Obesity
(2007-06-01)Abdominal obesity is associated with blunted growth hormone (GH) secretion. GH treatment in abdominally obese men reduces visceral adipose tissue (VAT) and improves the metabolic profile. The aim of this study was to ... -
GH/IGF-I axis regulation of cardiovascular and neuronal gene expression and function
(2009-08-24)Abstract Cardiovascular disease is a major cause of mortality in the Western world. Another important clinical condition is brain damage due to radiation therapy in cancer patients. This has neurological impairments ... -
Glucocorticoid-induced adrenal insufficiency
(2023-11-02)Background: Glucocorticoids (GCs) are effective in treating many diseases and are widely used. However, glucocorticoid treatment can down-regulate the hypothalamic-pituitary-adrenal axis and lead to glucocorticoid-induced ... -
Glucocorticoids - outcome in patients with glucocorticoid deficiency and Cushing's syndrome
(2012-05-15)Glucocorticoids (GCs) are steroid hormones that have a major impact on human metabolism and are essential for life. Chronic GC overexposure, called Cushing’s syndrome, is characterized by central obesity, muscle atrophy, ... -
Glycaemic control: evaluation of HbA1c as a risk factor and the effect of modern insulins in clinical practice
(2009-04-02)One of the ultimate goals of diabetes care is to minimise diabetic complications. When evaluating insulins it is important to understand what extent of improvements in glycaemic control is clinically relevant in preventing ... -
Gout - epidemiological studies on work outcomes, airborne risk factors and treatment patterns
(2022-11-10)The overall aim of the thesis was to describe the contemporary epidemiology and use of urate-lowering therapy (ULT) for gout in the Swedish region of Dalarna, to describe the impact of the disease with regard to sickness ... -
Graft-versus-Host Disease: Eosinophils, Chimerism and Clinical Features in Patients Undergoing Allogeneic Hematopoietic Stem Cell or Multivisceral Transplantation
(2016-05-12)Abstract Graft-versus-host disease (GVHD) is a potentially severe complication that may develop after allogeneic hematopoietic stem cell transplantation (HSCT). It can also occur after transplantation with isolated ...