Institute of Medicine / Institutionen för medicin
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Outcomes of invasive treatment in chronic limb-threatening ischaemia
(2023-10-03)Background In chronic limb-threatening ischaemia (CLTI), obstruction of the arterial blood flow causes ischaemic rest pain, ulcers or gangrene in the lower extremities. Patients with CLTI have a substantial risk of ... -
Long-term impact of exposure to sulfur mustard on mental health, quality of life, and lung function
(2023-09-04)Sulfur mustard is a highly harmful blistering chemical warfare agent with an alkylation ability that can affect multiple organs (skin, eyes and lungs) in the short and long term. Sulfur mustard’s long-term biopsychosocial ... -
Dietary patterns linked to symptoms in patients with a disorder of gut-brain interaction
(2023-08-18)Disorders of gut-brain interaction (DGBI) encompass a range of medical conditions characterized by gastrointestinal (GI) symptoms, in the absence of alarm features or organic diseases that explain the symptoms, after a ... -
Rho-GTPases in Rheumatoid Arthritis
(2023-05-24)The success of alleviating rheumatoid arthritis (RA) symptoms is complicated by both heterogeneity of the disease and lack of predictive markers to guide treatment options. Deregulated Rho-GTPases, a family of hydrolase ... -
Dietary intake, nutritional status and energy metabolism in individuals with anorexia nervosa - Effects of specialized eating disorder hospital treatment
(2023-05-23)Objective: Anorexia nervosa (AN) is a life-threatening condition affecting around 1% of the population. The aim of this thesis was to study nutritional aspects before and after specialized eating disorder hospital ... -
Vitamin D during pregnancy in relation to childhood growth, overweight and obesity
(2023-05-15)The aim of this thesis is to investigate the association between maternal vitamin D intake and status in pregnancy and the child´s growth and risk of overweight and obesity in childhood. Data from the Norwegian Mother, ... -
Primärvården och evidensen Evidensbaserad praktik i svensk offentlig primärvård från olika perspektiv
(2023-05-05)The development of information technology and growing insight into the limitations of the old paradigm of practicing medicine resulted in historical events that led to the emergence of evidence-based practice (EBP). ... -
NOTUM and RSPO3 in Bone - WNT signaling modulators regulating the skeleton
(2023-05-02)Osteoporosis is a skeletal disease affecting millions of people worldwide, often leading to fragility fractures and a decreased quality of life. There is an unmet medical need for new anabolic, bone building, treatments. ... -
Respiratory tract infections in primary care - aspects of diagnosis and treatment
(2023-04-26)Background Primary health care is accountable for most of the antibiotic prescriptions in humans. In Sweden, most of these antibiotics are used for respiratory tract infections, and pharyngotonsillitis (acute sore ... -
I själ och hjärta - Psykosociala faktorer och hjärt-kärlhälsa
Cardiovascular disease (CVD) is the leading cause of death in Sweden and worldwide. Although the prevalence is declining in the Western world there are signs of rising prevalence among the young. The overall aim of the ... -
Aspects of cardiac arrest in Sweden - studies based on the Swedish Registry for CPR
(2023-03-22)Background: Since the introduction of modern cardiopulmonary resuscitation (CPR) by Peter Safar in the late 1950s, a tremendous amount of work and scientific discovery has expanded our knowledge of cardiac arrest (CA), ... -
Priming and activation of neutrophils from blood and tissue
(2023-03-17)Inflammation is a powerful process, involved in many disease states, as well as in physiological situations. Neutrophils, the main characters of this thesis, are potent immune cells with the capacity to regulate inflammatory ... -
Psoriatic arthritis: cardiovascular risk factors, health-related quality of life and effects of weight loss treatment
(2023-03-15)Background: Psoriatic arthritis (PsA) is an inflammatory rheumatic disease, characterized by arthritis, dactylitis, enthesitis and sometimes axial disease. PsA is associated with several comorbidities and reduced health-related ... -
Arbetsskador och trafikskador: analys av historiska data
(GÖTEBORGS UNIVERSITET, 2023-02-25)Rapporten presenterar ett sätt att söka riskfaktorer för arbetsskador och trafik-skador i historiskt material. Korrelations- och regressionsanalyser har utförts med tidsserier av anmälda fall av arbetsskador och trafikskador, ... -
Diagnosis, mortality and professional life in patients with heart failure
(2023-02-22)Background: Heart failure (HF) is a common and severe disease with an increasing incidence among young adults. An emerging composite endpoint is home-time. Little is known, on how living with HF affects professional life. ... -
Roles of Androgens in Cardiovascular Physiology and Pathophysiology
(2023-02-20)ABSTRACT Atherosclerosis is the major underlying cause of cardiovascular disease, such as myocardial infarction (MI) and stroke, and these conditions are the leading causes of death both in Sweden and globally. The ... -
Translational genetics identifies a novel target to treat fatty liver disease
(2023-02-09)Fatty liver disease (FLD) is rapidly prevailing as the most common liver disease worldwide, with an estimated of one-quarter of the global population affected. Environmental and genetic determinants contribute to FLD ... -
Health economic aspects of stroke: stroke prevention and effects on spouses' healthcare consumption and income
(2023-01-23)The overall aim of this thesis was to investigate two health economic aspects of stroke: (i) the clinical and cost-effectiveness of stroke prevention with left atrial appendage occlusion (LAAO) among persons with atrial ... -
Factors of importance for work productivity in Irritable Bowel Syndrome
Disorders of gut-brain interaction (DGBI) are highly prevalent in the general population, and irritable bowel syndrome (IBS) is one of the most common DBGI. Having IBS, and many of the DGBI, can impact work life. However, ... -
Pain, gender norms and psychosocial resources. A critical appraisal of taken for granted ideas on men and women with pain
Background: Gender norms concerning pain are important to consider as they might lead to unequal treatment of men and women in health care. Aim: The overall aim of this thesis was to explore and describe gender norms ...