• Frailty in Older Adults in China -Trajectories, Determinants, and Impacts on Healthcare Utilization and Mortality 

  Guo, Yanfei (2024-09-26)

  Frailty, though not a disease in itself, often precedes the onset of illness and is frequently overlooked. Research has paid insufficient attention to frailty as a dynamic phenomenon, particularly its longitudinal changes. ...

• Determinants and risk factors for early risk stratification and optimal secondary pevention in ischemic heart disease 

  Sakalaki, Maria (2024-09-26)

  Background: Ischemic heart disease is the leading cause of death globally. To combat ischemic heart disease and its challenges we must improve secondary prevention for those already affected and prevent its onset in a ...

• Bacterial and Host Factors in Staphylococcus aureus Septic Arthritis 

  Hu, Zhicheng (2024-09-23)

  The intense battle against Staphylococcus aureus (S. aureus) infections, along with the ongoing struggle to develop new effective treatments, presents a major challenge for the healthcare system. This highly pathogenic ...

• Role of Gremlin1 and Bone Morphogenic Protein 4 (BMP4) in metabolic diseases 

  Khatib Shahidi, Roxana

  Gremlin1, a protein highly expressed in human adipocytes, plays a key role in the differentiation of precursor cells into white adipose tissue and is linked to insulin resistance in hypertrophic obesity. This study ...

• Respirable crystalline silica 

  Boers, Daisy (GÖTEBORGS UNIVERSITET, 2024-09-10)

  Crystalline silica is abundant in nature and used in a variety of industries, e.g., mining, farming, construction, foundry processes and production of glass, artificial stone, ceramics and cement. When cut or crushed, dust ...

• Food-related symptoms, dietary interventions, and importance of the gut microenvironment in IBS 

  Algera, Joost P. (2024-08-29)

  Irritable bowel syndrome (IBS) is characterized by chronic gastrointestinal (GI) symptoms, including abdominal pain and altered bowel habits i.e., constipation and diarrhea. The pathophysiology is complex and multifactorial ...

• Influence of Estrogen on Sex Bias in Inflammation 

  Barrett, Aidan (2024-08-19)

  The aim of this thesis was to investigate mechanisms underlying sex differences in inflammation and disease. In particular, the role of estrogen in regulating these mechanisms was explored. A secondary aim was to investigate ...

• Microbiota and Bone - Treatment Studies of Probiotics and Synbiotics on Osteoporosis in Mice 

  Lawenius, Lina (2024-08-19)

  Osteoporosis is a disease with low bone mass and an increased fracture risk. One in two women and one in four men in Sweden will experience an osteoporotic fracture. The aim of this thesis is to identify new gut microbiota-based ...

• Advancing Precision Medicine in Type 2 Diabetes through Machine Learning: Treatment Comparisons and Risk Predictions 

  Lugner, Moa (2024-06-05)

  Precision medicine holds significant promise for improving the management of type 2 diabetes, yet its implementation faces several challenges. This thesis aims to address existing gaps in precision medicine for type 2 ...

• Midwifery care providers' competencies in sub-Saharan Africa and global perinatal health outcomes 

  Nygaard Moller, Ann-Beth (2024-05-20)

  Background: Maternal and newborn mortality and morbidity remain critical global health issues, particularly in sub-Saharan Africa where many countries are struggling to meet the maternal and newborn related Sustainable ...

• Survival, prognostication and secondary prevention in cardiac arrest 

  Sultanian, Pedram (2024-05-17)

  Background: Sudden Cardiac Arrest (SCA) is a highly lethal medical emergency, caused by an abrupt cessation of cardiac function. Despite extensive research efforts, increased public awareness and systematic healthcare ...

• Management of Heart Failure with Focus on Inflammatory Myocardial Diseases: A Comparison between Cardiac Sarcoidosis and Giant Cell Myocarditis 

  Bobbio, Emanuele (2024-05-17)

  Background: The prevalence of advanced heart failure (HF) is rising, a condition portrayed by hemodynamic disturbances and poor prognosis. Heart transplantation (HTx) is a valid treatment option once other alternatives ...

• Phenotypes of Airway Diseases in Adults and Variation by Socioeconomic Status 

  Bashir, Muwada Bashir Awad (2024-05-16)

  Background: Lately, global prevalence of chronic obstructive airway diseases has risen, though some regions have seen stability. These diseases are heterogenous, have diverse manifestations and varying phenotypes. Ongoing ...

• Exploring the composition of the small airway lining fluid using breath analysis 

  Kokelj, Spela (2024-05-16)

  The mechanisms underlying the pathogenesis of chronic obstructive pulmonary disease (COPD), asthma and COVID-19 are not completely understood. The small airways, which are lined with the respiratory tract lining fluid ...

• Interprofessional simulation-based education and resilience-focused debriefing for improved teamwork 

  Amorøe, Torben Nordahl (2024-05-15)

  Interprofessional simulation-based education (IPSE) of healthcare students in interprofessional teamwork aims at improving patient safety, but issues related to trust and hierarchy may hamper learning interprofessional ...

• Peripheral artery disease and aortic complications in type 1 and type 2 diabetes mellitus 

  Avdic, Tarik (2024-05-14)

  Background: The connection between diabetes mellitus and atherosclerotic cardiovascular disease (ASCVD) complications, such as myocardial infarction and stroke, is well-established. However, the nature and extent of the ...

• Patients' experiences and effects of dietary changes when living with irritable bowel syndrome - Various impacts of dietary treatment 

  Weznaver, Cecilia (2024)

  Irritable bowel syndrome (IBS) is a complex disorder of gut-brain interaction. The causal explanations for this condition remain unclear, however, dietary factors appear to play a significant role in symptom generation and ...

• Exposure to air pollutants and birch pollen - pulmonary effects in allergic asthma 

  Lohman Haga, Susanna (2024-04-29)

  Allergies are on the rise and air pollution seems to be an important contributing factor. Exposure to birch pollen is a key trigger for both allergies and asthma, but whether there are synergistic effects between air ...

• Congenital heart disease and cancer: Cancer risk, risk factors and outcomes after cancer diagnosis 

  Karazisi, Christina (2024-04-25)

  Background: Congenital heart disease (CHD) is the most common congenital defect. The aim of this thesis was to study whether there is a higher cancer risk in CHD patients than in the general population (papers I and II), ...

• New-onset atrial fibrillation after coronary surgery: epidemiology, risk factors and long-term prognosis 

  Amar, Taha (2024-04-25)

  Background and aim: New-onset postoperative atrial fibrillation (POAF) is common following coronary artery bypass grafting (CABG). Evidence on its prognostic implications, risk-stratification methods, and factors influencing ...

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