Browsing Doctoral Theses from Sahlgrenska Academy by Title
Now showing items 21-40 of 2013
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Activation of professional phagocytes with emphasis on the formyl peptide receptor family
(2009-05-08)Phagocytic cells such as neutrophil granulocytes and monocytes are an essential part of our innate immune system and play an important role in the battle against pathogens. G-protein coupled receptors (GPCRs) and more ... -
Active Ageing a Path towards Ageing Well. Physical Functioning, Physical Activity, Falls Self-Efficacy and Social Participation in Community-Dwelling Elderly
(2016-01-21)The overall aim of this thesis was to study factors of importance for active ageing with a focus on physical functioning, physical activity, falls self-efficacy, health-related quality of life and social participation in ... -
Acute Achilles tendon rupture - The impact of calf muscle performance on function and recovery
(2017-11-17)There is an ongoing debate about the optimal treatment for patients with an acute Achilles tendon rupture. The overall purpose of this thesis was to acquire a greater knowledge of the way patients recover at different time ... -
Acute achilles tendon rupture. Evaluation of treatment and complications
(2009-04-17)The overall purpose of this thesis was to evaluate the treatment of patients with an acute Achilles tendon rupture with regard to complications, function and patient-reported outcome. Moreover, the purpose was to develop ... -
Acute Achilles Tendon Rupture. Outcome, Prediction and Optimized treatment
(2013-05-07)The optimal treatment for Achilles tendon rupture is the subject of debate and could be either surgical or non-surgical with various alternatives in terms of immobilization and rehabilitation. The purpose of this thesis ... -
Acute and chronic effects by stimulants on behavior and striatal neurotransmission in the rat
(2017-08-18)Nicotine and amphetamines are the most widely abused stimulants. The main aim of the studies in this thesis was to investigate how these two drugs of abuse affect distinct regions of the rat brain involved in development ... -
Acute and chronic peritonitis in peritoneal dialysis: neurogenic inflammation and citrate treatment
(2009-10-06)The prevalent problems associated with peritoneal dialysis (PD) are ultrafiltration failure and peritonitis. During PD the patient is sustained on a state of intraperitoneal inflammation, which over time impairs structure, ... -
Acute coronary syndrome and cardiac arrest in the elderly
(2015-05-11)The elderly are currently the fastest growing segment of clinical practice but the quality and quantity of the underlying scientific evidence to guide treatment is limited. In this thesis five different studies investigating ... -
Acute Coronary Syndromes. Characteristics, management and prognosis in relation to gender and type of syndrome
(2006-12-20)ABSTRACT Background: Acute coronary syndromes (ACS) represent a wide spectrum of conditions from ST-elevation myocardial infarction (STEMI) to unstable angina pectoris (UAP). Randomized trials tend to focus on ST-elevation ... -
Acute coronary syndromes. The prognostic importance of hypertension, diabetes and vectorcardiographic markers
(2013-11-11)Research questions: 1 Is hypertension and diabetes associated with the future risk of death, and recurrent manifestations of cardiovascular disease in acute coronary syndromes (ACS)? 2 How does myocardial ischemia affect ... -
Acute febrile illness in preschool children in Zanzibar - Infectious aetiologies, diagnosis and treatment
(2019-09-02)Background: A majority of the three million children in Africa that do not survive their fifth birthday die from infections that often start as a seemingly uncomplicated febrile illness. Primary health care workers ... -
Acute gastroenteritis in Rwandan children under five years of age investigated by real-time PCR
(2014-02-04)Acute gastroenteritis is a major cause of illness and death among children in developing countries. Knowledge about the aetiology is important to make the right priorities regarding preventive measures, and for the ... -
The acute osteoporotic vertebral compression fracture. Its natural course and characteristics.
(2009-02-21)Aim: The overall aim of this thesis was to investigate the natural course and the characteristics of the acute osteoporotic vertebral compression fracture in order to better understand and improve treatment for this type ... -
Acute respiratory infections among children in the Democratic Republic of Congo - nasopharyngeal pathogens, antibiotic resistance and vaccination
(2020-09-29)ABSTRACT Acute Lower Respiratory Infections (ALRI) remain a leading cause of morbidity and mortality among children in the Democratic Republic of the Congo (DR Congo). The pneumococcal conjugate vaccine PCV13 was ... -
Adaptation of ventricular repolarization to heart rate change in humans
(2021-10-01)Background: Life-threatening cardiac rhythm disturbances and sudden death are common manifestations of heart disease. Disturbances in electrical recovery (ventricular repolarization; VR) are important mechanisms behind ... -
Adaptive immune maturation in relation to allergic disease and vaccine responses in children
(2017-01-30)Adaptive immune maturation in children is likely the result of a complex interplay between both intrinsic and environmental factors, but surprisingly little is known about how early life immune maturation is related to ... -
Addison's Disease and Type 1 Diabetes Mellitus
(2018-05-18)Background: Patients with type 1 diabetes (T1DM) and patients with Addison’s disease (AD) need life-long replacement therapy with insulin and glucocorticoids (GCs), respectively. Both groups have reduced life-expectancy. ... -
Adherence to lipid-lowering medications and cardiovascular disease prevention in type 2 diabetes mellitus
(2018-11-07)Background and aims: Globally, cardiovascular disease (CVD) is the major cause of death among patients with type 2 diabetes mellitus (T2DM). Improved control of LDL cholesterol with lipid-lowering medications and patients’ ... -
Adipose tissue mitchondrial function is modulated by antioxidants
(2019-09-23)Antioxidants are widely used as reactive oxygen species (ROS) scavenging agents in experimental research and in conditions where oxidative stress plays a primary role. However, the effect of antioxidant supplementation ... -
Adipose tissue-derived serum amyloid A and adipose tissue macrophages in metabolic disease
(2013-11-29)Obesity is associated with a low-grade chronic inflammation with increased levels of proinflammatory markers in the circulation and local inflammation in the adipose tissue. In this thesis, two aspects of obesity-related ...