Browsing Doctoral Theses from Sahlgrenska Academy by Title
Now showing items 1159-1178 of 2013
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N-acetylaspartate in brain - studies on efflux and function
(2006-10-16)N-acetylaspartate (NAA) is an amino acid derivative present in high concentration in the brain. The function of NAA is still unsettled in spite of 50 years of research. The mainly neuronal synthesis and glial breakdown of ... -
Narcolepsy in children: Relationship to the H1N1 influenza vaccination, association with psychiatric and cognitive impairments and consequences in daily life
(2016-09-06)Background/aims: Narcolepsy is a lifelong sleep disorder with an onset most frequently in the second decade of life. The cardinal symptoms are excessive daytime sleepiness, cataplexy, hypnagogic and hypnopompic hallucinations ... -
Nasopharyngeal carcinoma: past, present and future directions
(2007-12-07)Nasopharyngeal carcinoma (NPC) is a rare disease in Sweden. The purpose of this thesis was to investigate the clinicopathological manifestations of the disease and its treatment outcomes in a cohort of Swedish NPC patients ... -
Natural course and long-term prognosis in idiopathic Normal Pressure Hydrocephalus - the effect of delayed surgery and clinical factors on outcome and survival
(2020-05-07)Idiopathic Normal Pressure Hydrocephalus, iNPH, causes gait and balance difficulties, urinary incontinence and cognitive decline in mainly older persons and is treatable by insertion of a cerebrospinal fluid diverting ... -
Natural History of Human Papillomavirus Infections and Other Sexually Transmitted Infections in Rwanda-Immunological Aspects of the Uterine Cervix
(2018-11-23)Objective: Cervical cancer stands for the predominant cause of cancer death among Rwandan women. Chronic Human Papillomavirus (HPV) infection constitutes the main risk factor. We here assessed the prevalence and incidence ... -
Natural killer T (NKT) lymphocytes regulate of intestinal tumor immunity
(2017-09-01)CD1d-restricted natural killer T (NKT) lymphocytes are known as potent early regulatory cells of immune responses, acting as a bridge between innate and adaptive immunity. While invariant NKT (iNKT) cells have a protective ... -
Navigating towards a self-determined daily life in old age. Experiences, instrument evaluation and explanatory factors.
(2015-05-18)Aim: The overall aim of this thesis was to explore self-determination in the context of community-dwelling older persons with different degrees of dependence in daily activities. Methods: Using a qualitative, grounded ... -
Närståendes besök hos patienter som vårdas på intensivvårdsavdelning
(2012-10-08)Aim: The overall objective of the present thesis was to describe and assess the importance and impact of visits by the patients’ families in an ICU, from patient and family perspectives, and to develop, from a hermeneutic ... -
Något som inte längre är - Distriktssköterskors yrkesutövning på vårdcentral ur ett genusperspektiv
(2007-05-23)District nurses have a long tradition of independence and influence over the content and organisation of their work, while the activities at their surgeries have been kept separate from other health services. Social and ... -
Neonatal invasive infections with focus on Group B streptococci
(2021-08-18)Invasive infections affect neonates with the risk of severe morbidity and death, and Streptococcus agalactiae (Group B streptococcus, GBS) remains one of the most common pathogens. The aim of this thesis was to assess ... -
Nerve conduction and vibrotactile perception thresholds in female computer workers and hand-arm vibration-exposed male manual workers
(2010-10-22)Upper limb pain and disability are common problems, especially among working populations. The overall aim of this thesis was to investigate peripheral nerve function in the upper limb by nerve conduction test and vibration ... -
Neural stam cells, TLX, and Neuroblastoma
(2014-09-19)Neuroblastoma (NB) is one of the most commonly diagnosed extracranial tumors in children below five years of age. Moreover, NB accounts for almost 12-15% of all childhood cancer related fatalities. To date, the origin of ... -
NEURAL STEM/PROGENITOR CELLS IN THE POST-ISCHEMIC ENVIRONMENT: Proliferation, Differentiation and Neuroprotection
(2007-06-04)Stroke is one of the leading causes of chronic disability and death in the Western world. Today, no treatment can repair the cellular loss associated with an ischemic lesion. However, the discovery and dynamic regulation ... -
Neurobehavioral correlates of disinhibitory psychopathology
(2020-11-20)Disinhibitory psychopathology refers to maladaptive behavioral expressions stemming from problems with impulse control. Despite a robust association with antisocial and criminal behavior, knowledge about the neurobehavioral ... -
Neurobiological markers for personality, inflammation and stress: A naturalistic study in knee arthroplastic patients
(2013-03-25)Background: Psychiatry has strived to identify biomarkers elucidating the underlying biological mechanisms behind different disorders, to help in diagnostics and to assess treatment effects. In forensic psychiatric ... -
The Neuroblastoma Genome and Epigenome - Patient Stratification and Identification of Candidate Genes
(2009-09-30)Neuroblastoma (NB) is a tumor of the sympathetic nervous system, and the most common extracranial tumor of childhood. The prognosis for high-stage NBs is still poor, with survival rates of about 35%. Side-effects of treatment ... -
Neurochemical and cognitive aftermaths of surgery - studies on short- and long-term effects of surgery and anesthesia
(2020-10-01)Background: Each year, around the world, more than 230 million patients have surgery. Improvements in healthcare have resulted in older and sicker patients undergoing surgical interventions. As a result, surgical safety ... -
Neurochemical and neuroendocrine reactions during non-neurological surgery
(2010-01-14)Abstract Objective: To study changes in serum and cerebrospinal fluid (CSF) proteins, monoamine metabolites and hormones during non-neurological surgery. Subjects and methods: Thirty-five patients without neurological or ... -
Neurofilaments as biomarkers of neuronal damage
(2019-09-24)Different neurodegenerative diseases have overlapping symptomatology and pathology and have thus become a challenge to modern medicine to achieve a correct diagnosis. The aim of the thesis was to evaluate the use of ... -
Neurogenic bladder and bowel dysfunction - incontinence and life situation in adolescents and adults with spina bifida
(2021-01-07)Neurogenic bladder and bowel dysfunction - incontinence and life situation in adolescents and adults with spina bifida Magdalena Vu Minh Arnell Department of Pediatrics, Institute of Clinical Sciences Sahlgrenska ...