Browsing Doctoral Theses from Sahlgrenska Academy by Title
Now showing items 824-843 of 2013
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ICT use and mental health in young adults. Effects of computer and mobile phone use on stress, sleep disturbances, and symptoms of depression
(2012-03-01)The overall aim of this thesis was to explore possible associations between information and communication technology (ICT) use and mental health symptoms among young adults. By “ICT” in this context is meant mainly computer ... -
Identification and characterization of progenitor populations in the human adult heart
(2014-01-17)Traditionally, the heart has been regarded as a non-regenerative organ. During the last 10 years, this notion has been challenged. By 14C measurements, it was calculated that at the age of 50, about 45% of all cardiomyocytes ... -
Identification and early detection of cancer patients in primary care
(2018-03-21)Aim The aim of this thesis was to investigate how general practitioners (GP) can identify patients in primary care with potential common cancers, at an early stage. It was also to design a risk assessment tool for colorectal ... -
Identification and imaging of lipids in tissues using TOF-SIMS
(2008-08-19)Introduction: Normal lipid metabolism in the adipose tissue, skeletal muscle and aortic wall is important for the physiological function of these tissues. Dyslipidemia that is often associated with intake of high energy ... -
Identification of esters in carious dentine Staining and chemo-mechanical excavation
(2017-02-17)Dental caries is clinically seen as a yellowish-brown discoloration that can be explained by the reactions between proteins and sugars resulting in Maillard products. However, the discoloration of carious dentine is an ... -
Identification of novel antibiotic resistance genes through the exploration of mobile genetic elements
(2020-05-12)Backgrounds and aims: The evolution of multi-resistant pathogens is seriously threatening our ability to provide modern healthcare. Many of the mobile resistance factors in clinics appear to originate from environmental ... -
Identification of novel growth hormone-regulated factors
(2009-11-27)The studies described in this thesis aimed to identify novel factors involved in the regulation of longitudinal growth and bone mineralization in response to growth hormone (GH) treatment. This was done by performing a ... -
Identification of stem cell factors - Novel protein-protein interactions and their functions
(2010-09-10)Embryonic stem (ES) cells provide an unlimited source of cells potentially useful for regenerative medicine, however, prior to clinical implementation, additional basic research is needed. This thesis is focused upon ... -
IL-6 and GLP-1 in body fat regulating parts of the CNS in healthy mice
(2016-01-29)It has previously been shown that mice lacking interleukin-6 (IL-6) develop mature onset obesity. The weight-suppressing effects of IL-6 have been assumed to be exerted at a central level, as supported by the fact that ... -
ILC2s and miRNA regulation in allergy and asthma
(2018-04-12)Asthma is a common respiratory disease that is characterized by chronic inflammation of the airways. In most asthmatic subjects, the immune response is driven by pro-inflammatory type 2 cytokines (interleukin (IL)-4, IL-5 ... -
Illness perception and fatigue after myocardial infarction
(2009-05-15)Treatment of myocardial infarction (MI) has undergone major advances in recent years, including reductions in mortality and hospital stays. To optimize patients’ recovery, secondary preventive strategies are important. ... -
Imaging of coronary artery function and morphology in living mice - applications in atherosclerosis research
(2007-05-04)Atherosclerosis in the coronary arteries is the major reason for myocardial infarction and cardiovascular death. In the clinic, several imaging systems make it possible to study coronary artery function and morphology ... -
Imaging of hip trauma - occult, suspect and concomitant fractures
(2016-04-05)Background: Between one and nine percent of all hip fractures are occult or suspect and further examinations with computed tomography (CT) and/or magnetic resonance imaging (MRI) are vital for further handling. Statistically ... -
Immigrants with heart failure- A descriptive comparative study of symptoms, self care, social support, care and treatment
(2007-11-27)Background: The current demographic profile in Sweden demonstrates blended ethnicities and cultures evolving through mass migration and resettlement. While it is acknowledged that cultural background affects, illness ... -
Immune escape in chronic leukemia
(2015-10-02)Reactive oxygen species (ROS) are produced by myeloid cells as a mechanism of defense against infection, but also to resolve inflammation, as ROS can induce cell death in T cells and NK cells. ROS production may also be ... -
Immune regulation by selective estrogen receptor modulators
(2015-04-30)At menopause, the levels of estrogen decline, leading to loss of estrogen-mediated protective effects on bone and an increased risk of osteoporosis. Hormone replacement therapy, containing estrogen, has been used for many ... -
Immune regulation of herpes simplex virus type 2 infection: Special emphasis on the transcription factor T-bet
(2007-01-03)Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the genital tract mucosa as well as local sensory neurons. It is the most common cause of genital ulcer disease in humans. The infection ... -
Immunization approaches and molecular signatures for mucosal immunity to primary and recurrent genital herpes
(2015-05-21)Genital herpes is most commonly caused by herpes simplex virus type 2 (HSV-2), and is a prevalent sexually transmitted infection worldwide. Despite numerous efforts, there is currently no licensed vaccine against the ... -
Immunofluorescence Investigation on Neuroendocrine Secretory Protein 55 (NESP55) in Nervous Tissues
(2008-03-31)The chromogranin family is a group of acidic, soluble, and heat-stable proteins widespread in various neuronal, neuroendocrine and endocrine tissues, where they are subcellullarly located in the secretory granules, ... -
Immunological and Genetic Markers Predicting Treatment Outcome in Hepatitits C Virus Infection
(2012-03-20)Hepatitis C is a blood-borne infection caused by the hepatitis C virus (HCV). A chronic infection, which develops in most infected subjects, may lead to liver cirrhosis with ensuing liver dysfunction and liver cancer. The ...