Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 497-516 of 636
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Remodelling of extracellular matrix in rectal cancer and preoperative radiotherapy
(2009-04-06)BACKGROUND Preoperative radiotherapy reduces local recurrence due to rectal cancer, but increases postoperative morbidity. The aim of this thesis was to study the impact of radiotherapy on extracellular matrix (ECM) ... -
Renal artery stenosis. Aspects of diagnosis and endovascular treatment.
(2018-03-23)Background. Renal artery stenosis (RAS) becomes haemodynamically significant when it reduces the arterial pressure below the threshold for autoregulation of renal perfusion. Physiological responses to reduced renal perfusion ... -
Renal denervation in patients with resistant hypertension
(2018-02-05)BACKGROUND Catheter-based renal denervation (RDN) is a potential modality in the treatment of patients with resistant hypertension (RH). The biological effects of RDN are not fully comprehended and studies examining its ... -
Renal function after transplantation of the liver and intestine
(2010-01-27)Background: Chronic kidney disease (CKD) after liver (LT) or intestinal (IT) transplantation may decrease patient survival. Calcineurin inhibitors (CNI) play a major role in its development. Aims: Describe long term renal ... -
Renal injury in liver transplantation clinical and mechanistic studies
(2023-04-19)ABSTRACT Background: Renal injury in liver transplantation (LT) is common and presents both as early and late insufficiency. These conditions are interconnected and have substantial impact on the long-term outcome. Multiple ... -
Renal perfusion, function and oxygenation after major surgery and in septic shock
(2017-11-24)Acute kidney injury (AKI) is a common and dreaded complication to severe illness and major surgery, with major impact on mor- bidity and mortality. The aim of this doctoral thesis was to increase the knowledge on renal ... -
Respiratory and esophageal morbidity in adults with repaired esophageal atresia
(2014-03-24)Background: Esophageal atresia (EA) often leads to persistent esophageal and respiratory symptoms, as well as impaired esophageal and lung function in adulthood. The reasons for this, and the connections between symptoms ... -
Revision anterior cruciate ligament reconstruction - current evidence, predictors and outcome
(2022-03-08)Despite extensive research in the field of anterior cruciate ligament (ACL) reconstruction, primary ACL reconstruction failure and a high re-rupture rate remain a problem. Far too many patients experience a second devastating ... -
Rhinosinusitis beyond the upper airways. Epidemiological aspects.
(2023-05-09)Rhinosinusitis (RS) is a prevalent, multi-factorial disease, including several subgroups of disease with different characteristics and pathophysiology. RS symptoms for more than 12 weeks are defined as chronic rhinosinusitis ... -
Risk Factors for Diabetic Ketoacidosis in Children
(2023-11-10)Background: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes. It is preventable if timely administration of sufficient amounts of insulin is initiated. A large proportion of children are ... -
Robotic Surgery for Endometrial Cancer
(2021-04-16)Endometrial cancer (EC) is the most common gynecological malignancy. A large proportion of patients present with the risk factors high age and obesity, which puts them at increased risk when undergoing surgery. The last ... -
The role of plant-food components in pelvic-organ cancer survivors - From feasibility to effects in randomized controlled dietary interventions
(2023-04-27)Background: The number of people who are surviving cancer is steadily growing. Dietary components have a potential role in preventing the side effects of treatment for pelvic-organ cancer, as well as tumor recurrence ... -
The role of sodium salicylate as a virulence inhibitor for soft tissue infections
(2022-08-16)Approximately 2% of the total population will suffer from chronic wounds during their lifetime. These wounds can last for years and are associated with considerable patient suffering and large socioeconomic costs. ... -
Roux-en-Y gastric bypass - clinical outcome and mechanisms of action
(2013-06-28)Roux-en-Y gastric bypass (gastric bypass) is an effective surgical technique for treating morbid obesity. The objective of this thesis is to increase knowledge of long-term outcomes of gastric bypass surgery and to elucidate ... -
Roux-en-Y gastric bypass as treatment of morbid obesity
(2013-04-03)Background and aims: Roux-en-Y gastric bypass (RYGB) is now a common treatment for obesity with well-documented effects on long-term weight reduction, health-related quality of life, obesity-related morbidity and mortality. ... -
Running-related injuries in recreational athletes.
(2021-11-09)Running as a form of physical activity continues to grow in popularity and is accompanied by a number of health benefits, but one of the greatest threats that challenge these benefits is running-related injuries. The overall ... -
Safety and quality aspects of IVF - neonatal and maternal outcomes following advanced techniques
(2020-04-15)Background: Singletons born following assisted reproductive technology (ART) have adverse neonatal outcome compared to singletons born following spontaneous conception (SC). Moreover, the women undergoing ART are at an ... -
Sagittal synostosis - surgical outcomes and long-term follow up
(2021-11-11)The overall aim of this thesis was to evaluate and compare surgical outcomes in patients with sagittal synostosis operated with the most commonly used surgical methods in Sweden: craniotomy combined with springs, pi-plasty, ... -
Screening for Hypertrophic Cardiomyopathy in Asymptomatic Children and Adolescents. Psychosocial consequences and impact on quality of life and physical activity.
(2011-10-11)The aim of this thesis was to describe the consequences of being diagnosed with hypertrophic cardiomyopathy (HCM) while being asymptomatic, taking into consideration psychosocial effects and medical aspects of diagnosis ... -
Selected aspects on improving the management of skin cancer
(2009-05-13)The constant rise of skin cancer incidence rates in Sweden is a problem which requires attention. Improved techniques for prevention, early detection and effective treatment are required to face this challenging task. The ...