Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 487-506 of 636
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Radiotherapy-induced late effects among female pelvic cancer survivors - sexual health, wellbeing, and impact of nurse-led interventions
(2022-09-01)This thesis addresses unmet needs concerning sexual health issues and low wellbeing in female cancer survivors treated with pelvic radiotherapy. The aim was to improve knowledge about sexual health, wellbeing and vaginal ... -
Recovery after surgically treated distal radius fracture - Aspects of evaluation and rehabilitation
(2022-11-14)BACKGROUND A distal radius fracture (DRF) is a common injury, occurring in both genders and during the entire life span, although it is most common in elderly women. An uncomplicated fracture is treated with a cast, but ... -
Recruitment of small size lungs - experimental studies
(2012-05-15)Background: Patients - both children and adults - undergoing anesthesia and mechanical ventilation rapidly develop atelectasis. Even more severe problems occur in patients with acute lung injury/acute respiratory distress ... -
Rectal Cancer and Quality of Life. Aspects on Communication and Patient Education
(2021-03-16)Background This thesis reports the results of three studies based on a pro-spective cohort study of an unselected population of patients with rectal cancer, and one study based on an exploratory study of a new patient ... -
Recurrent unexplained first-trimester miscarriage. Effects of acetylcalicylic acid, platelet aggregation and thyroid disease
(2019-10-18)Recurrent unexplained first-trimester miscarriage. Effects of acetylsalicylic acid, platelet aggregation and thyroid disease. Lennart Blomqvist, Department of Obstetrics and Gynecology, Institute of Clinical Sciences, ... -
Regenerative effects of mesenchymal stem cell-derived exosomes
(2019-02-06)Mesenchymal stem cells (MSCs) play pivotal roles for bone regeneration by virtue of their osteogenic differentiation ability and immunomodulatory capacity. Recently, secretion of exosomes/extracellular vesicles (EVs) has ... -
Regional fluxes of tissue plasminogen activator in porcine endotoxemia
(2007-10-30)Formation of fibrin clots in the microcirculation during severe sepsis contributes to organ failure, frequently involving the lungs and the splanchnic organs. Tissue type plasminogen activator, tPA, is the key activator ... -
Rehabilitation and outcomes after spasticity-correcting surgery in the upper limb
(2022-09-09)Background: The ability to perform everyday life activities is beneficial for one’s self-identity and contributes to human well-being. Enhancement of activity performance is therefore central in all forms of rehabilitation. ... -
Rejection and Immunosuppression at Uterus Transplantation: an experimental study in rodents.
(2009-12-01)Uterus transplantation is developed as a possible treatment for patients with absolute uterine factor infertility. There has been one attempt to transplant a human uterus, which however failed and more basic research is ... -
Relationship of Surgical Technique and Bony Morphology on Anterior Cruciate Ligament (ACL) Failure- Effect of Surgical Volume on Surgical Technique
(2024-04-15)Anterior cruciate ligament (ACL) injuries are becoming increasingly common and can have a detrimental effect on patients and their activities. Anatomic ACL reconstruction remains the gold standard for treatment. While ... -
Remodelling of extracellular matrix in rectal cancer and preoperative radiotherapy
(2009-04-06)BACKGROUND Preoperative radiotherapy reduces local recurrence due to rectal cancer, but increases postoperative morbidity. The aim of this thesis was to study the impact of radiotherapy on extracellular matrix (ECM) ... -
Renal artery stenosis. Aspects of diagnosis and endovascular treatment.
(2018-03-23)Background. Renal artery stenosis (RAS) becomes haemodynamically significant when it reduces the arterial pressure below the threshold for autoregulation of renal perfusion. Physiological responses to reduced renal perfusion ... -
Renal denervation in patients with resistant hypertension
(2018-02-05)BACKGROUND Catheter-based renal denervation (RDN) is a potential modality in the treatment of patients with resistant hypertension (RH). The biological effects of RDN are not fully comprehended and studies examining its ... -
Renal function after transplantation of the liver and intestine
(2010-01-27)Background: Chronic kidney disease (CKD) after liver (LT) or intestinal (IT) transplantation may decrease patient survival. Calcineurin inhibitors (CNI) play a major role in its development. Aims: Describe long term renal ... -
Renal injury in liver transplantation clinical and mechanistic studies
(2023-04-19)ABSTRACT Background: Renal injury in liver transplantation (LT) is common and presents both as early and late insufficiency. These conditions are interconnected and have substantial impact on the long-term outcome. Multiple ... -
Renal perfusion, function and oxygenation after major surgery and in septic shock
(2017-11-24)Acute kidney injury (AKI) is a common and dreaded complication to severe illness and major surgery, with major impact on mor- bidity and mortality. The aim of this doctoral thesis was to increase the knowledge on renal ... -
Respiratory and esophageal morbidity in adults with repaired esophageal atresia
(2014-03-24)Background: Esophageal atresia (EA) often leads to persistent esophageal and respiratory symptoms, as well as impaired esophageal and lung function in adulthood. The reasons for this, and the connections between symptoms ... -
Revision anterior cruciate ligament reconstruction - current evidence, predictors and outcome
(2022-03-08)Despite extensive research in the field of anterior cruciate ligament (ACL) reconstruction, primary ACL reconstruction failure and a high re-rupture rate remain a problem. Far too many patients experience a second devastating ... -
Rhinosinusitis beyond the upper airways. Epidemiological aspects.
(2023-05-09)Rhinosinusitis (RS) is a prevalent, multi-factorial disease, including several subgroups of disease with different characteristics and pathophysiology. RS symptoms for more than 12 weeks are defined as chronic rhinosinusitis ... -
Risk Factors for Diabetic Ketoacidosis in Children
(2023-11-10)Background: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes. It is preventable if timely administration of sufficient amounts of insulin is initiated. A large proportion of children are ...