Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi by Title
Now showing items 351-370 of 480
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Population Pharmacokinetic-Pharmacodynamic Modelling of Antimalarial Treatment
(2014-11-28)Malaria is one of the most important tropical diseases, with hundreds of millions of cases every year. The current recommended treatment is an artemisinin based combination therapy (ACT), which has shown good efficacy. ... -
Population-based studies of brain tumor surgery: surgical outcome and prognostic factors
(2020-08-27)Neurosurgery is the cornerstone in the treatment of a majority of brain tumors. Surgery can sometimes cure or delay tumor progression. However, surgery is associated with risks, and adequate information about the anticipated ... -
Postural balance, anxiety and motor function after stroke, at a very early supported discharge with continued rehabilitation
(2020-10-23)The overall aim of this thesis was to investigate postural balance, anxiety and motor function the first year after stroke and whether postural balance, anxiety and motor function was different at the intervention of Very ... -
Pre-, peri- and postnatal influences on ophthalmologic outcome - a study on children born after intracytoplasmic sperm injection (ICSI) and children born preterm
(2009-05-13)The aims of the present study were to investigate the effects of prenatal factors in children born after intracytoplasmic sperm injection (ICSI) and peri- and postnatal factors in children born preterm on visual function ... -
Pre/Peri/Earl-Life Exposures and Early Child Neurodevelopment: Results from the Japan Environment and Children's Study (JECS)
(2023-08-18)Background: Combinations of genetic and environmental factors contribute to aetiologies of neuropsychiatric problems and neurodevelopmental disorders (NDDs) in intricate manners. Among the environmental factors, exposures ... -
Precision in neuropsychology. Four challenges when using simplified assumptions
(2019-05-16)Cognition comprises all thought processes, from perception to memory. Neuropsychological tests are the gold standard (= best way) to measure cognition. However, clinical assessment may at times have to rely on simplified ... -
Preclinical investigations of GlyT-1 inhibition as a new concept for treatment of alcohol dependence
(2011-02-02)Alcohol addiction and abuse is a main contributor to the global burden of disease and is a high public health priority. Alcohol addiction is a chronically relapsing neurobiological disorder affecting multiple neurotransmitter ... -
Prediagnostic and comorbidity factors in preschool children with autism
(2015-08-31)The aim of the thesis was to investigate Autism Spectrum Disorder (ASD) diagnosed in the early years from different angles; screening, load of coexisting disorders, outcome at routine developmental surveillance, and to ... -
Predictors of long-term outcome after severe traumatic brain injury
(2013-12-20)Aim: A complex interaction between several factors may influence and explain the variance in outcome after traumatic brain injury (TBI). The overall aim of this thesis was to explore, in individuals with severe TBI, the ... -
Predictors of Outcome after Anterior Cruciate Ligament Reconstruction
(2018-03-02)An anterior cruciate ligament (ACL) injury is one of the most common injuries to the knee joint. It is also one of the most researched areas within sports medicine, orthopedics and physical therapy. The goal of this thesis ... -
Predictors of severe kidney disease in long-term lithium treatment
(2024-04-22)The thesis aims to advance the understanding of severe chronic kidney disease in lithium-treated patients through four observational studies in which subjects were recruited from the Sahlgrenska University Hospital laboratory ... -
The prefrontal cortex and information processing : nitric oxide signaling studied in an animal model of schizophrenia
(2008-11-28)The prefrontal cortex has been extensively linked to several cognitive domains that are severely compromised in schizophrenia. It has therefore become a key region for studies on the disabling cognitive dysfunction commonly ... -
Pregnancy-related pelvic girdle pain management. Tailored physiotherapy treatment strategies anchored in women's experiences and expectations
(2024-01-11)Introduction: Pregnancy-related pelvic pain (PGP) affects over half of all pregnant women. This pain can significantly impact daily activities and limit the ability to move freely, leading to reduced physical activity, ... -
Prodromal Cognitive Signs of Dementia
(2009-04-24)The increase in proportion of elderly worldwide, coupled with the fact that increasing age is a primary risk factor for dementia, have fuelled the efforts to unveil the warning signs of dementia. Although important ... -
Progesterone receptor-mediated effects on apoptosis in periovulatory granulosa cells
(2006-11-28)The most common fate of developing ovarian follicles is demise due to a process known as atresia. Regulation of atresia is dependent on the developmental stage of the follicles, resulting in a continuous reduction of the ... -
Proteomic strategies for analysis of cerebrospinal fluid in neurodegenerative disorders
(2008-04-04)ABSTRACT There is a great need for biomarkers to diagnose neurodegenerative disorders, such as the cognitive disorders Alzheimer’s disease (AD) and frontotemporal dementia (FTD). Cerebrospinal fluid (CSF) is in contact ... -
Psychiatric symptoms and disorders in old age: prevalence, course and diagnostic thresholds
(2015-09-04)The aim of this thesis was to study the epidemiology of some psychiatric disorders, as well as their corresponding subthreshold symptoms, in order to explore the border between psychopathology and normality in the general ... -
Psychological outcomes during rehabilitation after ACL reconstruction - and implications for second ACL injury
(2024-04-24)An anterior cruciate ligament (ACL) injury is a common knee joint injury. An ACL injury is typically managed through surgical reconstruction of the ligament, followed by rehabilitation. For patients treated with ... -
Psychological stress in relation to dementia and brain structural changes
(2012-09-03)Psychological stress has been recognized as an increasing public health problem with serious consequences in both physical and mental health. Women reported a higher prevalence of psychological stress, especially in midlife. ... -
Purinergic effects in the rat urinary bladder. Functional studies of cyclophosphamide treatment on afferent and efferent mechanisms
(2013-02-27)Pathological conditions in the lower urinary tract are common and have a great impact on the quality of life for the patients suffering from such disorders. In this thesis cyclophosphamide (CYP)-induced cystitis, a ...