Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Title
Now showing items 499-518 of 609
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Role of GPIbαlpha Clustering and N-linked Carbohydrates in the Clearance of Refrigerated Platelets
(2006-10-06)The thesis focuses on understanding the mechanisms by which: 1) the macrophage alphaM-subunit recognizes betaN-acetylglucosamine (betaGlcNAc) residues on the von Willebrand factor receptor complex ((GPIbalpha,beta/IX)2V ... -
The Role of Gut Dysfunction and Nutritional Factors in Liver Cirrhosis
(2007-03-14)Malnutrition is a common finding in patients with liver cirrhosis. Malnutrition has been shown to be associated with increased morbidity and mortality. Its pathogenesis remains unclear but both poor dietary intake and ... -
The role of physical activity on bone density and bone geometry in men
(2010-04-14)THE ROLE OF PHYSICAL ACTIVITY ON BONE DENSITY AND BONE GEOMETRY IN MEN Introduction: Several studies indicate that peak bone mass, reached during the third decade in life, is an important determinant of osteoporosis later ... -
The Role Of Serum Amyloid A In Inflammatory Disease - Proinflammatory Mediator Or Inert Biomarker?
(2010-03-31)Abstract: Neutrophils are phagocytes of the innate immune system with prominent roles in host defense and are also believed to be important in autoimmune diseases such as rheumatoid arthritis (RA) by accumulating in inflamed ... -
The role of the gut microbiota in central energy balance regulation
(2022-04-11)The gut microbiota can affect development and metabolism in the host. Today, much is still unknown regarding the effects of the gut microbiota on central energy balance regulation. We used mouse models to determine the ... -
Roles of Androgens in Cardiovascular Physiology and Pathophysiology
(2023-02-20)ABSTRACT Atherosclerosis is the major underlying cause of cardiovascular disease, such as myocardial infarction (MI) and stroke, and these conditions are the leading causes of death both in Sweden and globally. The ... -
Roles of PI3-kinase and ARAP2 in regulating glucose metabolism
(2016-04-19)Insulin signaling is mediated by a complex, highly integrated network which functions to control multiple metabolic and growth processes throughout the organism. A key enzyme in the insulin signaling network is ... -
Safety leadership in the construction industry
(2018-01-02)The overall aim of this thesis was to identify and describe essential components of safety leadership behavior in the construction industry in Sweden and Denmark. The methods used were semi-structured interviews, cross-sectional ... -
Samverkan vid vårdplanering för patienter med komplexa behov – ett mellanorganisatoriskt triangeldrama
(2019-05-22)Aims: The overall aim of this thesis was to deepen the knowledge of collaboration in care planning across healthcare provider boundaries for patients with complex care needs. Specific aims were: to highlight specialist ... -
Self-perceived Psychological Health and Vascular Changes in Childhood
(2007-06-08)Self-perceived Psychological Health and Vascular Changes in Childhood AKADEMISK AVHANDLING som för avläggande av medicine doktorsexamen vid Sahlgrenska akademin vid Göteborgs universitet kommer att offentligen ... -
Self-tolerance in collagen induced arthritis
(2013-04-29)Rheumatoid arthritis (RA) is an autoimmune chronic disease that results in damage to tissues throughout the body due to the inability of the immune system in these patients to discriminate between self-tissues and foreign ... -
Sex hormones and cardiovascular risk in men and women. The Skaraborg Project
(2014-02-04)The general aim of this thesis was to explore the associations between sex hormones and high blood pressure in men and women and to investigate their further role in the development of acute myocardial infarction particularly ... -
Sex steroid hormones - roles in adaptive immunity and vascular pathology
(2013-12-20)The prevalence of autoimmune diseases is higher in women than men, while for cardiovascular disease, there is a male predominance. The sexual dimorphism of autoimmune and cardiovascular diseases probably relates to a number ... -
Sex steroid metabolism and body composition
(2009-04-30)Background: The bioactive androgens testosterone (T) and dihydrotestosterone (DHT) regulate bone and fat mass in men. The effects of androgens are largely determined by the rate of their synthesis and inactivation. ... -
Shoulder function and activity limitations in patients with early rheumatoid arthritis
(2013-11-22)Patients with rheumatoid arthritis (RA) have impaired physical function which can lead to difficulties with daily activities. Despite improved pharmacological treatment, patients with early RA report difficulties with ... -
Skilled birth attendant services in Nepal: overcoming barriers to utilization
(2017-05-18)Background Skilled birth attendants (SBAs) provide important services that improve maternal and newborn health and reduce maternal and newborn mortality. Utilization and coverage of SBA services reveal wide disparities ... -
Sleep apnea and atrial fibrillation: cause or comorbidity?
(2023-10-19)Background: Obstructive sleep apnea (OSA) and atrial fibrillation (AF) are common conditions, associated with morbidity and mortality. Both OSA and AF often go undetected. It has been suggested that OSA may be a modifiable ... -
Sleep disorders, sleepiness and the risk of traffic accidents
(2014-04-10)The aim of this thesis was to identify the prevalence of sleep disorders, mainly obstructive sleep apnea (OSA), among public transport operators (PTO´s). Further to assess the risk of motor vehicle accident (MVA) in a group ... -
Smoking and T cell co-stimulation in rheumatoid arthritis
(2019-04-18)In this thesis I investigated if smoking limits the co-stimulatory system of CD8+ T cells in rheumatoid arthritis (RA). I took special interest in the co-inhibitory receptor PD-1 and its ligand PD-L1. Blood samples from ... -
Socioeconomic aspects of lifestyle and women's health: a primary care and population perspective
(2020-03-05)Aims: To estimate growth characteristics and socioeconomic factors in relation to over-weight/obesity among 4-year-old children. To explore whether a primary care lifestyle programme reached and engaged socioeconomically ...