Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Title
Now showing items 388-407 of 609
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On the effects of obesity treatment
(2021-05-12)Aim: In this thesis the effects of bariatric surgery in individuals with type 1 diabetes (T1D) will be assessed as well as the effects of surgery on risk for heart failure (HF) and atrial fibrillation (AF) in individuals ... -
On the regulation of immune responses to dietary and self antigens
(2010-02-04)Regulatory mechanisms are necessary to avoid the misdirected aggressive immune responses responsible for the pathology seen in autoimmunity and allergy. Thymic-derived CD4+CD25+ regulatory T cells are indispensible for ... -
On the role of gut microbiota in intestinal physiology and hepatic metabolism
(2017-03-03)The gut microbiota, a complex and dynamic community of microbes in the mammalian gut, has coevolved with us for ample time providing mutual benefits. However, mechanistic knowledge of these has been limited, but are now ... -
On viral infections in lung transplant recipients
(2017-12-15)Viral infections are the most common type of infection in humans. Lung transplantation (LTx) recipients are exceptionally susceptible to infections in general, and the short- and long- term effects tend to be more detrimental. ... -
Open heart surgery and its consequences for well-being - the perspectives of patients, relatives and health care professionals
(2008-05-23)Introduction: Adjustment to open heart surgery (OHS) is complex and necessitates multidimensional explanations. The surgery does not always provide the desired outcome, which can contribute to reduced well-being among ... -
Optimizing the early treatment of a threatening myocardial infarction
(2013-01-09)Acute myocardial infarction is the single most common cause of death for both women and men in Sweden. Great efforts have, over the years, been made to improve immediate treatment and care of acute coronary syndromes. Through ... -
Osteoporosis in SLE
(2008-12-03)As the treatment of Systemic Lupus Erythematosus (SLE) has become more effective the focus has partly shifted from main concern of short term morbidity and survival to long term complications such as osteoporosis. The aims ... -
Ostructive lung disease - occupational exposures, smoking and airway inflammation
(2017-02-06)Abstract Obstructive lung disease is a group of respiratory diseases characterized by airways obstruction. Among them the more frequent are asthma and chronic obstructive pulmonary disease (COPD). Obstructive lung ... -
Outcome of Graves disease
(2020-02-05)Graves' disease (GD) is an autoimmune condition with elevated thyroid hormone levels and symptoms suggesting an affected brain. These symptoms often resolve with treatment but, for some patients, GD results in a long period ... -
Outcomes in treated hypertensive men - a follow-up during three decades
(2007-05-24)Objectives: To analyse survival, cause specific mortality and cardiovascular morbidity in relation to cardiovascular risk factors, to investigate the prevalence of type 2 diabetes and the cardiovascular risk this constitutes ... -
Outcomes of invasive treatment in chronic limb-threatening ischaemia
(2023-10-03)Background In chronic limb-threatening ischaemia (CLTI), obstruction of the arterial blood flow causes ischaemic rest pain, ulcers or gangrene in the lower extremities. Patients with CLTI have a substantial risk of ... -
Overweight and obesity in the young and old: Prevalence, prevention and eating behavior
(2007-03-09)ABSTRACT Background: During the last 25 years the prevalence of overweight and obe-sity has increased dramatically, both in developed and developing countries. The World Health Organization is declaring it an epidemic. ... -
Pain, gender norms and psychosocial resources. A critical appraisal of taken for granted ideas on men and women with pain
(2023-01-10)Background: Gender norms concerning pain are important to consider as they might lead to unequal treatment of men and women in health care. Aim: The overall aim of this thesis was to explore and describe gender norms ... -
Parathyroid Hormone Hyper- and Hypoparathyroidism Effect of Treatment and Long-term Follow-up Studies
(2024-01-10)Background: High or low parathyroid hormone (PTH) can be challenging in diagnosis and treatment. The prevalence and natural history of normocalcemic hyperparathyroidism (nHPT) are still not known. The knowledge gap regarding ... -
Parental time pressure and financial stress - Challenges for mental health of Nordic children and adolescents
(2014-12-02)Mental health problems are a significant public health concern affecting approximately 10-20% of children and adolescents worldwide. Parents’ conditions and experiences are important in determining children’s circumstances, ... -
Participation in everyday life. Very old persons' experiences of daily occupation, occupation of interest and use of assistive devices.
(2007-05-24)The overall aim of the present thesis was to examine, extend and deepen the understanding of very old persons’ experience of participation in everyday life from an occupational perspective. The thesis consists of four ... -
Passive sampling of PAHs and some trace organic compounds in occupational and residential air: needs, evaluation and limits
(2010-05-11)Human exposure to elevated levels of polycyclic aromatic hydrocarbons (PAHs) and trace organic compounds (e.g. PCB, OCP, PBDE) can be related to negative health effects. This raises demands of exposure measurements to be ... -
Patent Foramen Ovale (PFO) and cryptogenic stroke or transient ischemic attack: a follow-up study
(2014-11-24)Aims: The overall aim of this thesis was to study the long-term clinical outcomes in terms of survival, complications, recurrent stroke or transient ischemic attack (TIA), and quality of life in a group of patients with ... -
Pathogenesis of Obesity and Effects of Treatment. Clinical and Molecular Studies on Body Fat, Energy Balance, and Weight Loss.
(2009-06-29)Obesity is common and related to many health problems including various forms of cancer. The condition arises from the imbalance between food intake and energy expenditure, and is strongly influenced by genetic factors. ... -
Pathophysiological role and clinical relevance of cytokines in hypertensive heart failure. A combined clinical and experimental study
(2007-12-06)Although mortality due to heart failure has decreased significantly in the last decade since the introduction of ACE-inhibitors and β-adrenergic receptor blockers in the management of heart failure, chronic heart failure ...