Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 183-202 of 636
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Epidemiology, diagnostics and treatment of non-melanoma skin cancers
(2018-02-23)Skin cancer, including malignant melanoma and non-melanoma skin cancer (NMSC), is a growing problem due to the increasing incidence in Sweden and in other Caucasian populations. NMSCs are diagnosed as often as all other ... -
Epigenetic influence on cardiovascular protective mechanisms in vivo: explorations of t-PA release and extracellular vesicle genetic content
(2015-05-18)ABSTRACT Background: Ischemic heart disease is one of the leading causes of death globally. This thesis explores endogenous mechanisms protecting against myocardial ischemia in context of epigenetics (changes in gene ... -
EPILEPSY AND CHILDHOOD AUTISM - with special reference to neuropsychiatric aspects on surgical interventions for medically intractable epilepsy
(2009-01-12)Epilepsy is much more common in individuals with autism than in the general population. The extent to which epilepsy influences the outcome of autism is poorly understood. Many children with medically intractable epilepsy ... -
Erectile dysfunction in clinical practice. - With special focus on the correlation to myocardial infarction, lower urinary tract symptoms (LUTS), treatment cost and optimization -
(2008-04-21)The purpose of this thesis was to study and evaluate some aspects of Erectile Dysfunction (ED) in clinical practice, with special focus on the correlation to myocardial infarction, LUTS (lower urinary tract symptoms), ED ... -
Esophagitis: Aspects on bacteriology, pathophysiology and symptomatology
(2018-05-18)Gastroesophageal reflux disease (GERD) and eosinophilic esophagitis (EoE) are the two most common diseases causing inflammation of the esophagus, namely, esophagitis. GERD and EoE are different in many aspects, but ... -
Estimation of clinical dose distributions for breast and lung cancer radiotherapy treatments
(2016-11-07)The overall aim of this thesis was to investigate the uncertainties in the dose distribution determined at the treatment planning stage. The work has been based on the main hypothesis that the way of determining dose at ... -
Evaluation of a structured physiotherapy treatment model for patients with lumbar disc herniation
(2013-04-03)Symptoms from lumbar disc herniation are common in the general population. Many discs heal spontaneously and the patient’s symptoms cease. When people have severe pain and sciatica, the recommendation is to start with ... -
Evaluation of absorbed dose uncertainty in modulated radiotherapy plans
(2022-10-10)The purpose of this work was to develop and evaluate methods to meet the challenges of quality control (QC) for modulated radiotherapy plans. It was shown that nine of 15 intensity modulated radiotherapy (IMRT) plans, ... -
Evaluation of regulator of G-protein signaling 2 (RGS2) at different stages of prostate cancer - Significance and clinical potential
(2019-05-15)Prostate cancer (PC) is often a slow-growing and symptom-free disease with good prognosis. However, a substantial number will progress, ultimately metastasize if left untreated and finally kill the patient. The standard ... -
Evaluation of surgical outcomes in craniosynostosis
(2013-04-02)Background: A continuous and objective evaluation of surgical outcomes must be an integrated part of the technical development. The present thesis has the ambition to innovate the evaluation of surgical results allowing ... -
Ex Vivo Lung Perfusion - experimental and clinical studies
(2018-05-07)Background: Ex vivo lung perfusion (EVLP) has since its introduction in clinical practice experienced a rapid expansion and made more organs available for transplantation. Different protocols and strategies have been ... -
Exahaled NO and small airway function in asthma and cystic fibrosis
(2010-05-28)Background: Asthma and cystic fibrosis (CF) are chronic inflammatory airway disorders known to involve the peripheral airways. Non-invasive tests sensitive to peripheral airway function and inflammation are therefore of ... -
Excess skin after bariatric surgery - patients' perspective and objective measurements
(2015-05-04)Most of the world's population lives in countries where overweight and obesity kills more people than underweight. The only effective treatment is found to be bariatric surgery. Excess skin is an undervalued, negative ... -
Experiences of IVF - from a patient perspective
(2014-05-23)The overall aim of this thesis was to assess the quality of life and quality of care from a patient perspective, in relation to IVF treatment. This was done by: - assessing infertile couples’ short-term emotional ... -
Experiences of living with cleft lip and palate - a gender perspective
(2021-11-10)The primary aim of this thesis was to investigate the influence of gender on the CL/P population with regard to treatment, self-reported appearance, psychosocial adjustment, and subjective experiences. Study I, a retrospective ... -
Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker
(2014-09-05)Background: Colorectal cancer (CRC) is one of the most common malignancies, and the only reliable treatment option for cure is surgery. Method: Quantitative real-time polymerase chain reaction was used to analyze the ... -
Experimental Models of the Human Peritoneal Environment: Effects of TGF-beta and Hyaluronan
(2008-04-04)BACKGROUND Post surgical adhesion formation is still an unsolved problem and occurs when there is an imbalance between fibrin deposition and fibrin clearing capacity in the abdominal cavity. Transforming growth factor ... -
Experimental models with specific approaches to augment human fetal liver cell engraftment
(2014-05-27)Experimental models with specific approaches to augment human fetal liver cell engraftment Pradeep Patil Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg Background: ... -
Experimental studies on ovarian cryopreservation and transplantation
(2011-05-09)Around 8% of all cancer victims are below 40 years of age and the survival after cancer treatment during childhood and reproductive years has increased considerably to be around 80% today. The clinical field of fertility ... -
Exploring mechanisms of insulin secretion regulators using C. elegans
(2022-11-09)Diabetes mellitus is a group of disorders characterized by disrupted glucose homeostasis. Diabetes is one of the most dangerous diseases worldwide since it affects currently more than 500 million people. The pathogenesis ...