Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper by Title
Now showing items 12-31 of 636
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The acute osteoporotic vertebral compression fracture. Its natural course and characteristics.
(2009-02-21)Aim: The overall aim of this thesis was to investigate the natural course and the characteristics of the acute osteoporotic vertebral compression fracture in order to better understand and improve treatment for this type ... -
Adolescent and young adult cancer survivors - body image and sexual health
(2018-04-25)Background Adolescent and young adult cancer survivors constitute a group in society of which the numbers are increasing. To optimize rehabilitation efforts, we need to understand the possible physical and psychological ... -
Advancements in DSC and BOLD perfusion imaging: Acquisition, analysis and clinical application
(2023-10-31)This thesis is focused on perfusion MRI techniques and topics related to image acquisition, analysis and clinical applications. The first half of the thesis is focused on dynamic susceptibility contrast (DSC) MRI, a technique ... -
Advances in MRI based radiation therapy - Bringing MRl-only and multiparametric methods towards clinical applications
(2023-01-12)MRI data have the advantage of being excellent in soft tissue contrast, therefore having an increasing imaging role in external radiation therapy (RT). Lately, attention has been directed towards MRI-only workflows, with ... -
Alpha-radioimmunotherapy with At-211: Evaluations and imaging on normal tissues and tumors
(2011-04-21)Alpha-radioimmunotherapy (alpha-RIT) is an internal conformal radiotherapy at the cellular level using alpha-particle emitting radionuclides. Alpha-particles have a very short range in tissues (<100 micrometer) and high ... -
Analysis of body motions based on optical markers. Accuracy, error analysis and clinical applications.
(2010-11-08)This thesis aims to evaluate the influence of soft-tissue artefacts on analyses of body motions based on optical markers. A second aim is to apply instrumented gait analysis in clinical situations. Introduction: Instrumented ... -
Anatomic anterior cruciate ligament reconstruction - aspects of surgical technique
(2016-04-19)Anatomic anterior cruciate ligament (ACL) reconstruction is a concept that has gained in interest and it aims to more effectively restore native ACL anatomy and function. Despite extensive research on the topic, the optimal ... -
Anatomic anterior cruciate ligament reconstruction - current evidence and future directions
(2012-03-30)Injury to the anterior cruciate ligament (ACL) is one of the most common orthopedic diagnoses. It is also one of the most researched areas in orthopedic surgery, with well over eleven thousand publications. Despite this, ... -
Androgen-Independent Prostate Cancer - studies on angiogenesis and ADAMTS1
(2009-10-27)Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer since prostate tumors initially are dependent on androgens for growth. However, most tumors will eventually relapse and grow in a ... -
Antecedents of Cerebral Palsy in children born at term - according to subtype, motor severity and accompanying impairments
(2016-02-05)Aims: To explore antecedents of cerebral palsy (CP) according to subtype, severity of motor impairment and accompanying impairments (epilepsy and/or cognitive impairments) in relation to neuroimaging patterns. Material ... -
Anterior Cruciate Ligament Reconstruction - Early predictors of outcome
(2019-03-21)The rupture of the anterior cruciate ligament (ACL) is a serious injury, often resulting in functional instability and increased laxity of the knee joint. Patients suffering an ACL injury run the risk of further ... -
Anterior Cruciate Ligament Reconstruction - Graft failures, surgical techniques and patient-reported outcome measures
(2016-05-06)Injuries to the anterior cruciate ligament (ACL) can result in increased joint laxity, which often ends participation in competitive sports and may, in the medium to long term, lead to degeneration of the knee. The occurrence ... -
Anterior cruciate ligament reconstruction surgery, aspects of graft choice, graft fixation and bone mineral loss
(2013-10-25)The aim of this thesis was to measure bone mineral changes in the calcanei, hips and lumbar spine of patients reconstructed with bone-patellar tendon-bone (BPTB) or hamstring tendon (HT) autografts following ... -
Anterior cruciate ligament reconstruction using semitendinosus and gracilis autograft. Evaluation of the clinical outcome, radiographic findings, histology and biochemistry
(2015-05-18)The present thesis focuses on different aspects of anterior cruciate ligament (ACL) reconstruction using hamstring tendon (HT) autografts. In Study I, two groups of patients were compared. One group underwent surgery in ... -
Anterior cruciate ligament reconstruction: long-term outcome in adults and adolescents. Clinical results, health-related quality of life, radiographic findings and boone mineral assessments
(2015-09-10)The aim of this thesis was to measure health-related quality of life (HRQoL) and assess pre-operative factors predicting good outcome of HRQoL after anterior cruciate ligament (ACL) reconstruction. Furthermore, to specifically ... -
Anterior Cruciate Ligament Reconstruction; Randomized Trials, Register Studies and Experimental Analysis of Knee Laxity
(2013-05-02)The aim of this thesis was to evaluate the short- and mid-term outcome of Anterior Cruciate Ligament (ACL) reconstruction, with special emphasis on surgical techniques, type of autograft and the influence of gender, using ... -
Antibiotic therapy as single treatment of acute appendicitis
(2012-05-29)ABSTRACT BACKGROUND Appendectomy has been the established treatment of acute appendicitis during the last century, regarded as a simple and safe procedure, although hampered with postoperative complications and increased ... -
Aortic valve imaging - Towards new standards in prosthetic valve endocarditis
(2016-04-28)Background: Aortic prosthetic valve endocarditis (PVE) is a disease with high mortality, and diagnosis is difficult. Transesophageal echocardiography (TEE) has been the mainstay imaging modality in the diagnostic workup, ... -
Apoptotic mechanisms in the neonatal brain following hypoxia-ischemia
(2011-10-28)Introduction: Neonatal encephalopathy is often perinatally acquired and caused by hypoxia-ischemia (HI). Brain injury develops with a delay, over 12-48 hours, after the insult. Hypothermia, an established neuroprotective ...