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Antibiotic therapy as single treatment of acute appendicitis


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Title: Antibiotic therapy as single treatment of acute appendicitis
Authors: Hansson, Jeanette
E-mail: jeanetteh@ltkalmar.se
Issue Date: 29-May-2012
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Clincial Sciences. Department of Surgery
Parts of work: I. Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients. Hansson J, Körner U, Khorram-Manesh A, Solberg A, Lundholm K Br J Surg 2009;96(5): 473-481.
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II. Antibiotics as first line therapy for acute appendicitis: evidence for a change in clinical practice. Hansson J, Körner U, Ludwigs K, Johnsson E, Jönsson C, Lundholm K World J Surg 2012 May 9 (Epub ahead of print)
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III. A proposed model to select patients who may benefit from antibiotic therapy as the first line treatment of acute appendicitis at defined probability. Hansson J, Khorram-Manesh A, Alwindawe A, Lundholm K Submitted for publication

IV. Evaluation of procalcitonin as marker to predict efficacy in treatment of acute appendicitis following institution of antibiotic therapy for cure. Hansson J, Körner U, Lundholm K Submitted for publication
Date of Defence: 2012-06-15
Disputation: Fredagen den 15 juni 2012, kl 9.00, Hjärtats aula, Sahlgrenska Universitetssjukhuset/Sahlgrenska.
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: appendicitis
antibiotic therapy
appendectomy
procalcitonin
Abstract: ABSTRACT BACKGROUND Appendectomy has been the established treatment of acute appendicitis during the last century, regarded as a simple and safe procedure, although hampered with postoperative complications and increased standard mortality. Modern research has indicated that selected patients with acute appendicitis can be treated by antibiotic therapy alone. The aim of this thesis was therefore to explore antibiotic therapy as single treatment of acute appendicitis in unselected adult patient... more
ISBN: 978-91-628-8463-5
URI: http://hdl.handle.net/2077/28960
Appears in Collections:Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses from Sahlgrenska Academy

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