Browsing Sahlgrenska Academy / Sahlgrenska akademin by Title
Now showing items 2177-2196 of 2863
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Radiation-induced dysphagia in head and neck cancer - risk structures and methodological aspects
(2019-08-19)Background/Aims: Swallowing difficulties are common after radiation therapy (RT) in head and neck cancer (HNC). The overall aim of this thesis was to address radiation-induced late dysphagia with regard to investigating ... -
Radiobiological effects of alpha-particles from Astatine-211: From DNA damage to cell death
(2011-05-26)ABSTRACT In recent years, the use of high linear energy transfer (LET) radiation for radiotherapeutic applications has gained increased interest. Astatine-211 (211At) is an -particle emitting radionuclide, promising ... -
Radiobiological effects of the thyroid gland - transcriptomic and proteomic responses to 131l and 211At exposure
(2015-04-08)Radionuclides are widely used in medicine. 131I is one of the most employed radionuclides and is administered to patients either bound to tumor targeting molecules or as halide to target the thyroid or thyroid cancer. 211At ... -
Radiographic follow-up analysis of Brånemark® dental implants
(2008-05-15)Radiography plays an important role in clinical routine practice and in research projects evaluating dental implants, among them Brånemark® System. Presence of a peri-implant radiolucency has been used in studies as a ... -
Radiological and Clinical Changes in Idiopathic Normal Pressure Hydrocephalus: MRI, Vascular factors and Clinical Symptoms as Markers of Pathophysiology and Prognosis
(2020-01-15)Idiopathic normal pressure hydrocephalus (iNPH) is a treatable, neurological disorder affecting the elderly population causing gait, balance, cognitive and micturition impairments. Treatment results in a clinical improvement ... -
Radiological evaluation of esophageal function in dysphagia with special emphasis on achalasia
(2008-10-03)In idiopathic achalasia, degeneration of the inhibitory innervation of the esophageal smooth muscle results in absence of primary peristalsis and in incomplete relaxation of the lower esophageal sphincter (LES). All ... -
Radiotherapy and voice rehabilitation in laryngeal cancer: Effects on quality of life and voice function
(2015-02-27)The overall aim of the thesis was to describe the effects of radiotherapy following laryngeal cancer on health-related quality of life (HRQL) and voice function as well as to assess the efficiency of voice rehabilitation. ... -
Radiotherapy-induced late effects among female pelvic cancer survivors - sexual health, wellbeing, and impact of nurse-led interventions
(2022-09-01)This thesis addresses unmet needs concerning sexual health issues and low wellbeing in female cancer survivors treated with pelvic radiotherapy. The aim was to improve knowledge about sexual health, wellbeing and vaginal ... -
En rapport om studiemiljö, stress och hälsa bland Sahlgrenska akademins studenter
(Arbets- och miljömedicin, Göteborgs universitet, 2017-10-02)Rapporter från både Göteborgs universitets Akademihälsa och Sahlgrenska akademin Studentkår har uppmärksammat en hög förekomst av överbelastning och psykisk ohälsa bland studenter vid Sahlgrenska akademin. Därför beslöt ... -
Re-evaluation of the hypothesis that LTP has two temporal phases and that the late phase is protein synthesis-dependent
(2015-02-19)Long-term potentiation (LTP) is an activity-dependent increase in synaptic efficacy that is most studied in the hippocampus and that is considered a cellular substrate for learning and memory. Accepting the belief that the ... -
Re-interventions after endovascular aortic repair: clinical and experimental studies
(2016-04-25)Background: Endovascular aortic repair (EVAR) has lower morbidity and mortality than open surgery. Late complications and re-interventions are more common, however, and the timing of different re-interventions and their ... -
Reactive gliosis in the injured brain: The effect of cell communication and Nrf2-mediated cellular defence
(2011-02-18)Stroke and other brain injuries trigger an extensive glial cell response referred to as reactive gliosis. Reactive gliosis is characterized by hypertrophic and proliferating astrocytes, proliferating microglia and NG2-positive ... -
Real-time PCR studies of genotypes, mutations and replication of hepatitis B virus
(2012-02-10)Infection with hepatitis B virus (HBV) is an important cause of liver disease and affects 350 million people worldwide, causing 600,000 deaths/year. Treatment includes interferon and nucleoside analogues (NAs) such as ... -
Receptor Cross-talk and Neutrophil Function
(2013-05-08)The chemotactic recruitment of neutrophils, the most abundant white blood cell in human circulation, to sites of infection and inflammation, is dependent upon a gradient of chemoattractants released from cells at the ... -
Recidivism and Static-99R risk assessments in a Swedish cohort of mentally disordered sexual offenders
(2021-05-07)Mentally disordered sexual offenders (MDSOs) constitute a heterogeneous offender subgroup presenting a wide range of clinical comorbidity. The recidivism rates for such a disparate subgroup vary substantially, which ... -
Recombinant mucin-type proteins as tools for studies on the interactions between Helicobacter pylori and its carbohydrate receptors
(2020-06-11)Glycan-protein interactions are important in pathogen adhesion and infections. H. pylori has adhesins which enables it to bind to glycans on the gastric mucosa and, in the long run, cause gastric cancer. The reported current ... -
Recombinant Mucins with Tailored Glycosylation as Bacterial Toxin Inhibitors
(2015-11-23)Multivalent carbohydrate-based ligands that can inhibit biomedically important protein–carbohydrate interactions have therapeutic potential. One of the important targets for therapeutic intervention is the binding processes ... -
Reconstruction of the RVOT with a conduit: Lifetime follow up
(2016-01-15)Background: The use of a conduit is an established surgical method for reconstruction of the right ventricular outflow tract in congenital heart disease. The most commonly used conduit is a homograft. Its limited ... -
Reconstructive upper limb surgery in patients with cervical spinal cord injury. Evaluation of postoperative treatments and examination of applicability of the Klein-Bell ADL Scale
(2009-02-03)Aims: Studies I & II: To describe and evaluate postoperative deltoid-triceps protection of tendon elongation and long-term clinical follow-up after tenodesis to the IP joint of the thumb. Study III: To examine and explore ... -
Recovery after surgically treated distal radius fracture - Aspects of evaluation and rehabilitation
(2022-11-14)BACKGROUND A distal radius fracture (DRF) is a common injury, occurring in both genders and during the entire life span, although it is most common in elderly women. An uncomplicated fracture is treated with a cast, but ...