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Now showing items 51-59 of 59
Epithelial signatures in respiratory disease
(2021-11-25)
The epithelium of the human airways protects us against harm and helps
maintain immune homeostasis. In respiratory diseases such as asthma and
COPD, the functions of the epithelium are altered and can cause or contribute
to ...
Neurobiological markers for personality, inflammation and stress: A naturalistic study in knee arthroplastic patients
(2013-03-25)
Background: Psychiatry has strived to identify biomarkers elucidating the underlying biological mechanisms behind different disorders, to help in diagnostics and to assess treatment effects. In forensic psychiatric ...
Exhaled particles for monitoring of airway inflammation
(2016-11-17)
Non-invasive collection methods suitable for studying the composition of the respiratory tract lining fluid (RTLF) in small airways are currently not readily available. The overall aim of this thesis was to contribute to ...
The effect of intra-abdominal local anaesthetics following major gynaecological surgery. Clinical and experimental studies
(2020-05-18)
Background: Local anaesthetics (LA), in addition to inhibition of pain signalling, also have anti-inflammatory
properties. In vitro studies have demonstrated anti-proliferative and cytotoxic effect of
LAs on cancer cells ...
Irradiation-induced injury to the juvenile brain -Roles of sex and inflammation
(2013-11-14)
Radiotherapy is commonly used in the treatment of pediatric malignancies, but unfortunately it is associated with negative side effects, both long-term and short-term. Negative side effects following cranial irradiation ...
Effects of antiresorptive agents on inflammation and bone regeneration in different osseous sites - experimental and clinical studies
(2014-09-29)
ABSTRACT
The biological mechanisms involved in bone regeneration in osteoporotic bone and the effect of antiresorptive drugs in relation to surgically inserted biomaterials are not fully understood. Improved osseointegration ...
Peri-implantitis and periodontitis. Experimental and clinical studies
(2015-03-24)
Peri-implantitis is an increasing problem in implant dentistry. The current series of studies employed a translational approach with the aim to compare peri-implantitis and periodontitis lesions and evaluate the influence ...
The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury
(2022-01-13)
The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common ...
Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery
(2020-05-15)
Background: The biological mechanisms and physiological pathways of pregnancy maintenance and timing of delivery are complex and multifactorial. Pregnancy clocks, partly controlled by timing mechanisms linked to fetal ...