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Defense-related inhibition of sympathetic nerve activity: Insights from neuroimaging and monozygotic twins on related cortical processes and clinical potential


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Title: Defense-related inhibition of sympathetic nerve activity: Insights from neuroimaging and monozygotic twins on related cortical processes and clinical potential
Authors: Jonsson Eskelin, John
E-mail: john.jonsson.eskelin@gu.se
Issue Date: 27-May-2021
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Neuroscience and Physiology. Department of Clinical Neuroscience
Parts of work: 1. Lundblad, L. C., Eskelin, J. J., Karlsson, T., Wallin, B. G., & Elam, M. (2017). Sympathetic Nerve Activity in Monozygotic Twins: Identical at Rest but Not During Arousal. Hypertension, 69(5), 964-969.
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2. Riaz, B., Eskelin, J. J., Lundblad, L. C., Wallin, B. G., Karlsson, T., Starck, G., Lundqvist, D., Ooostenveld, R., Schneiderman, J. F., & Elam, M. Brain structural and functional correlates to defense-related inhibition of muscle sympathetic nerve activity in man. Manuscript

3. Eskelin, J. J., Lundblad, L. C., Wallin, B. G., Karlsson, T., Riaz B., Lundqvist, D., Schneiderman, J. F., & Elam, M. Simultaneous recordings of EEG and MSNA during somatosensory stimulation – prospects of a non-invasive biomarker for defense-related sympathetic inhibition. Manuscript
Date of Defence: 2021-06-18
Disputation: Fredagen den 18 juni 2021, kl. 13.00, sal 2119, Hus 2, Hälsovetarbacken, Arvid Wallgrens Backe, Göteborg. https://gu-se.zoom.us/j/63037687043?pwd=WHJaVDJrMTNEcWJta2RwbTIyWERvQT09
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: microneurography
MEG
EEG
MRI
blood pressure
defence reaction
cortical autonomic network
Abstract: This thesis investigates a physiological phenomenon observed in the peripheral sympathetic nervous system in response to various stressors and tries to bring it closer to clinical research. Sudden surprising stimulation can evoke a transient inhibition of sympathetic nerve activity to blood vessels in the human body which is also predictive of the blood pressure response. The underlying medical hypothesis is that this may be important for long term blood pressure. In Paper I we investigate the p... more
ISBN: 978-91-8009-370-5 (PRINT)
978-91-8009-371-2 (PDF)
URI: http://hdl.handle.net/2077/68073
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi

 

 

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