Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi by Title
Now showing items 95-114 of 480
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Cognitive profiles of vascular and neurodegenerative MCI
(2008-06-30)The objective of the thesis was to investigate the cognitive profiles of different types of mild cognitive impairment (MCI) and follow their course over time. Would it be possible to differentiate between “benign” and ... -
Cognitive, emotional and psychosocial functions after resective epilepsy surgery
(2022-05-02)Epilepsy surgery is a potentially curing treatment for a selected group of patients with drug-resistant focal epilepsy. Cognitive side-effects after temporal lobe resections (TLR) are well documented but it is still difficult ... -
Cold feet in children with neurological disorders
(2009-09-11)These studies focused on presence of cold feet in children with neurological disorders and raised the questions: Does acupuncture affect skin temperature? Are cold feet a general symptom in children with neurological ... -
Collaborative challenges in integrated care: Untangling the preconditions for collaboration and frail older people's participation
(2018-10-26)Introduction: Frail older people often have comprehensive and complex care needs involving different caregivers and professionals. Deficits in integrated caretaking often result in hospital readmission. Aim: The aim of ... -
Colonic barrier function in ulcerative colitis - Interactions between ion and mucus secretion
(2012-05-07)Anion and mucus secretions have traditionally been looked upon as two separate parts of the epithelial defense system. The importance of anion secretion has been attributed to its role in creating the driving force for ... -
Community dwelling person’s perspective on functioning after stroke
(2014-08-29)Abstract Stroke is the second most common cause of death worldwide and the most common cause of long-term disability in adults. Disability following stroke results from the interaction between persons with impairments and ... -
Comorbidity across childhood-onset neuropsychiatric disorders
(2015-04-22)Background: Attention-Deficit/Hyperactivity Disorder (ADHD), and Autism Spectrum Disorders (ASDs) are clinically found to be comorbid with each other and with other psychiatric conditions to a greater extent than what is ... -
Comorbidity of inflammatory diseases in the lower urinary tract - the link between chronic prostatitis and bladder dysfunction
(2022-10-18)Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disease in men that currently lacks satisfactory pharmacological treatment alternatives. The aim of this thesis was to investigate the effects of CP/CPPS ... -
Comparative in vivo pharmacology of dopidines A novel class of compounds discovered by phenotypic screening
(2015-09-10)Dopidines are a novel class of dopamine (DA) modulating compounds, developed to provide improved treatment of a range of neurodegenerative and psychiatric disorders that are currently managed to a large extent with ... -
Comprehending the Comprehensive Geriatric Assessment. Feasibility, outcomes and experiences of frail older people
(2020-06-04)ABSTRACT Despite existing knowledge on how to approach frail people in health care, the care they receive is commonly not designed to meet their complex needs and support them in maintaining their activities of daily ... -
Conditional and non-conditional reward-related responses to alcohol - nicotinic mechanisms
(2006-11-14)The mesolimbic dopamine system is believed to mediate the positive reinforcing and rewarding effects of addictive drugs by increasing dopamine levels in its terminal area, the nucleus accumbens (nAc). Nicotinic acetylcholine ... -
Congenital muscular torticollis
(2008-10-01)Aim: The purpose of these studies was to undertake a survey of functional and cosmetic status in children treated for congenital muscular torticollis (CMT), to examine validity and reliability of the Muscle Function Scale ... -
Corneal transplant outcome- a Swedish register
(2008-11-24)Aim. The aim of this study was to present different aspects of the outcome after corneal transplantation based on data from the Swedish Cornea Register. Papers. The first paper describes the register and gives descriptive ... -
Creating opportunities for cultural awareness in occupational therapy: An example from Latin America
(2016-05-09)Aim: to explore how awareness of cultural issues is being applied within occupational therapy to address some of the challenges relating to professional education and practice. Methods: In Study I an integrative literature ... -
CSF biomarker panels. Focus on synaptic pathology
(2022-08-18)Fluid biomarkers of neuropathological features are important clinical tools in diagnostics and patient monitoring of neurodegenerative diseases. For the most prevalent cause of dementia, Alzheimer’s disease (AD), several ... -
CSF biomarkers in idiopathic normal pressure hydrocephalus- Diagnostics and pathophysiology
(2019-05-23)Idiopathic normal pressure hydrocephalus (iNPH) is a disease of the elderly with enlarged ventricles despite a normal CSF pressure. Clinically, iNPH presents with gait- and balance disturbances, cognitive decline and ... -
CSF biomarkers reflecting beta-amyloid and axonal pathology in Alzheimer's disease and related conditions
(2011-11-18)Cerebrospinal fluid (CSF) biomarkers may be used to identify and monitor pathological processes in the central nervous system. CSF biomarkers in Alzheimer’s disease (AD) include β-amyloid 42 (Aβ42), total-tau (T-tau) and ... -
Cytochrome P450 2E1 - relevance for central dopamine neurotransmission and Parkinson's disease
(2008-08-25)Introduction: The enzyme cytochrome P450 2E1 (CYP2E1) has been found in dopamine (DA) containing brain regions that are of relevance for Parkinson’s disease (PD), and is known to generate reactive oxygen species (ROS), ... -
Cytochrome P450 enzymes affected by artemisinin antimalarials-pharmacokinetic and pharmacogenetic aspects
(2008-11-03)With more than 500 million cases and at least 1 million deaths each year, malaria is a major global health problem. The main problem with malaria control is the emerging drug resistance among parasites causing the infection. ... -
Cytokines and lipids in pregnancy – effects on developmental programming and placental nutrient transfer
(2010-08-12)Metabolic disturbances, in particular those associated with nutritional challenges, that take place during development, both in utero and early postnatal life, have long-lasting health consequences on an individual. The ...