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Re-interventions after endovascular aortic repair: clinical and experimental studies
(2016-04-25)
Background: Endovascular aortic repair (EVAR) has lower morbidity and mortality than open surgery. Late complications and re-interventions
are more common, however, and the timing of different re-interventions and their ...
Urinary Clara cell protein and alpha 1-microglobulin – biomarkers of changes in kidney and airway function
(2010-04-13)
Validated biomarkers are useful tools for screening large populations. The benefit of screening
may be improved risk assessment or early indications of adverse effects before detection or onset
of symptoms. Screening is ...
Defining orellanine as treatment of advanced renal cell carcinoma
(2014-03-28)
Renal cancer causes over 100,000 annual deaths worldwide, and the incidence is increasing. Clear cell renal cell carcinomas (CCRCC), constituting 75% of renal cancer, are known for their high metastatic frequency and ...
Contemporary aspects of health and performance among young adult women and men in Sweden
(2010-05-17)
The overall aim of this thesis was to improve our understanding of contemporary aspects of health and performance among young adult women and men in Sweden. Cultural and structural changes in society have resulted in new ...
Functional Modulation of the Pattern Recognition Formyl Peptide Receptors in Neutrophils - Lipopeptides - allosteric modulators of G-protein coupled receptors
(2017-01-20)
G-protein-coupled receptors (GPCRs), which are the largest class of cell-surface receptors, are involved in a range of physiologic processes and pathologies, making this a highly interesting group of proteins as targets ...
Cardiovascular risk factors in renal artery stenosis
(2017-05-11)
Renovascular hypertension (RVH) caused by atherosclerotic renal artery stenosis (ARAS) is
one of the most common forms of secondary hypertension. The prognosis for patients with
RVH is much worse compared to patients ...
Sex hormones and cardiovascular risk in men and women. The Skaraborg Project
(2014-02-04)
The general aim of this thesis was to explore the associations between sex hormones and high blood pressure in men and women and to investigate their further role in the development of acute myocardial infarction particularly ...
Aspects of Abnormal Glucose Regulation in Various Manifestations of Coronary Artery Disease
(2012-02-03)
Background
Diabetes is common among patients with coronary artery disease (CAD) and is associated with an approximate doubling of the mortality risk in this patient population. Prediabetes, an intermediate glycometabolic ...
Diabetes and obesity in primary health care - a condition beyond physiological factors
(2011-11-18)
Aims: The objectives of this thesis are to illustrate how obese and normal-weight individuals with type 2 diabetes (T2DM) experience their health status and health care interactions and to highlight the diabetes team ...
Androgen receptor signaling mechanisms in bone
(2018-12-13)
Osteoporosis is a common age-related disease that increases the risk of fractures. Androgens are crucial for bone health in males. Although a substantial part of the effects of androgens on the skeleton is mediated via ...