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Urinary Clara cell protein and alpha 1-microglobulin – biomarkers of changes in kidney and airway function

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Title: Urinary Clara cell protein and alpha 1-microglobulin – biomarkers of changes in kidney and airway function
Authors: Andersson, Lena
Issue Date: 13-Apr-2010
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Medicine. Department of Public Health and Community Medicine
Parts of work: I. Andersson L., Lundberg PA., and Barregard L Methodological aspects on measurement of Clara cell protein in urine as a biomarker for airway toxicity, compared with serum levels. J Appl Toxicol 2007 Jan; 27: 60–66.

II. Andersson L., Haraldsson B., Johansson C., and Barregard L Methodological issues on the use of urinary alpha-1-microglobulin in epidemiological studies. Nephrol Dial Transplant 2008; 23: 1252–1256.

III. Barregard L., Sällsten G., Andersson L., Almstrand AC., Gustafson P., Andersson M., and Olin AC Experimental exposure to wood smoke: effects on airway inflammation and oxidative stress. Occup Environ Med 2008; 65: 319–324.

IV. Andersson L., Preda I., Hahn-Zoric M., Hanson LÅ., Jodal U., Sixt R., Barregard L., and Hansson S Urinary proteins in children with urinary tract infection. Pediatr Nephrol 2009; 24: 1533–1538.

V. Andersson L., Strålin K., and Barregard L Clara cell 16kDa protein in patients with community-acquired pneumonia. Manuscript
Date of Defence: 2010-04-23
Disputation: Fredagen den 23 april 2010, kl. 9.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: biomarker
Clara cell 16 kDa protein (CC16)
alpha 1-microglobulin (A1M)
ambient air pollution
renal function
Abstract: Validated biomarkers are useful tools for screening large populations. The benefit of screening may be improved risk assessment or early indications of adverse effects before detection or onset of symptoms. Screening is valuable in studies of environmental exposures and their effects on human health, for example after exposure to air pollution and toxic metals in our daily environment. The overall aim of this thesis was to optimize sampling of urinary Clara cell 16 kDa protein (CC16) and al... more
ISBN: 978-91-628-8065-1
Appears in Collections:Doctoral Theses / Doktorsavhandlingar Institutionen för medicin
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses from Sahlgrenska Academy



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