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Attenuation of acute inlammatory responses by surface nanotopography


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Title: Attenuation of acute inlammatory responses by surface nanotopography
Authors: Hulander, Mats
E-mail: mats.hulander@cmb.gu.se
Issue Date: 4-Oct-2012
University: University of Gothenburg. Faculty of Science
Institution: Department of Cell and Molecular Biology ; Institutionen för cell- och molekylärbiologi
Parts of work: I Mats Hulander, Jaan Hong, Marcus Andersson, Frida Gervén, Mattias Ohrlander, Pentti Tengvall and Hans Elwing Blood interactions with noble metals: Coagulation and immune complement activation Applied material & interfaces (1) 2009, 1053-1062
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II Mats Hulander, Anders Lundgren, Mattias Berglin, Mattias Ohrlander, Jukka Lausmaa and Hans Elwing Immune complement activation is attenuated by surface nanotopography International journal of nanomedicine (6) 2011, 2653-2666
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III Anders Lundgren, Mats Hulander, Joakim Brorsson, Malte Hermansson, Hans Elwing, Olle Andersson, Bo Liedberg and Mattias Berglin Adsorption of gold nanoparticles and its application towards chemically functionalized gradient nanopatterns Submitted

IV Mats Hulander, Lars Faxälv, Anders Lundgren, Mattias Berglin and Hans Elwing The use of a gradient in surface nanotopography to study influence of nanoparticle size and inter-particle distance on platelet adhesion and activation Submitted
Date of Defence: 2012-10-26
Disputation: fredagen den 26 oktober 2012 kl 13.00 i föreläsningssalen vån 5 Biotechhuset Arvid Wallgrens backe 20, Göteborg
Degree: Doctor of Philosophy
Publication type: Doctoral thesis
Keywords: Gold nanoparticles, nanotopography, gradient nanotopography, immune complement, platelets
Abstract: The interaction between biology and non-viable surfaces is crucial for many organisms and cells. For example, bacterial cells need to adhere to mineral surfaces in the soil, plants climb and adhere to walls and marine organisms produce adhesives to cling to underwater rocks etc. In the human body, tissue needs to firmly adhere to the mineral surface of bone, but also to foreign materials when for example a biomaterial is implanted. The knowledge of how biology interacts with surfaces is hence im... more
ISBN: 978-91-628-8563-2
URI: http://hdl.handle.net/2077/30285
Appears in Collections:Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för kemi och molekylärbiologi

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