Toxic metals and metalloids are emerging as major environmental pollutants, having ecological consequences as well as being linked to a broad range of degenerative conditions in animals, plants and humans. While the toxicity ...

Saccharomyces cerevisiae Snf1 and its mammalian homolog, AMPK, are members of a protein kinase family present throughout the Eukaryotic kingdom. AMPK plays an essential role in different cellular processes and is involved ...

All biological systems have to cope with a wide range of metals that are present in the environment. Metals can be essential or beneficial for life, inert or non-essential and toxic, often depending on their chemical form ...

Cells are constantly subjected to perturbations. Whether these are extracellular or intracellular, they can be detrimental to cellular fitness. The cell has evolved elaborate systems and mechanisms that allow it to remain ...

The budding yeast Saccharomyces cerevisiae AMP-activated protein kinase/SNF1 is a member of a highly conserved protein family present in all eukaryotes. Snf1 regulates energy homeostasis; in yeast, it is best-known for its ...

The SNF1/AMP-activated protein kinase (AMPK) belongs to a family of energy sensors that is conserved in all eukaryotes. Activated by ATP depletion, AMPK plays a vital role in restoring the energy balance by enhancing ...

Cadmium and arsenite are common environmental pollutants; considered highly toxic and pose a substantial threat to human health with millions of people worldwide being at risk of exposure. Cadmium and arsenite are carcinogenic ...

Arsenic and cadmium are two toxic heavy metals that occur naturally in bedrock. Arsenic is found in high concentrations in certain areas and can contaminate groundwater, leading to exposure through drinking water and crop ...