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The role of progesterone in the regulation of ciliary activity in the fallopian tube


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Title: The role of progesterone in the regulation of ciliary activity in the fallopian tube
Authors: Nutu, Magdalena
E-mail: magdalena.nutu@fysiologi.gu.se
Issue Date: 13-Nov-2009
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Neuroscience and Physiology. Department of Physiology
Parts of work: I. Membrane progesterone receptor gamma: tissue distribution and expression in ciliated cells in the fallopian tube. Magdalena Nutu, Birgitta Weijdergård, Peter Thomas, Christina Bergh, Ann Thurin-Kjellberg, Yefei Pang, Håkan Billig, D.G. Joakim Larsson. Molecular Reproduction and Development 2007; 74: 843 - 850
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II. Distribution and hormonal regulation of membrane progesterone receptors beta and gamma in ciliated epithelial cells of mouse and human fallopian tubes. Magdalena Nutu, Birgitta Weijdergård, Peter Thomas, Ann Thurin-Kjellberg, Håkan Billig, D.G. Joakim Larsson. Reproductive Biology and Endocrinology 2009; 7:89
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III. Rapid effects of progesterone on ciliary beat frequency in the mouse fallopian tube Anna Bylander*, Magdalena Nutu*, Rikard Wellander, Mattias Goksör, Håkan Billig, D.G. Joakim Larsson. Manuscript *Both authors contributed equally to this manuscript
Date of Defence: 2009-12-02
Disputation: Onsdagen den 2 december 2009, kl. 9.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3, Göteborg
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: progesterone
progesterone receptor
non-genomic progesterone receptor
ciliated cells
fallopian tube
gamete transport
ciliary activity
ciliary beat frequency
reproduction
fertility
Abstract: The overall aim of this thesis was to investigate the distribution and regulation of membrane progesterone receptors (mPRs) that may be involved in regulating ciliary activity in the fallopian tube. The fallopian tube serves to transport the egg and spermatozoa to achieve fertilization. Later, the formation of the pre-embryo is thought to result from the movement of cilia in the epithelium and the muscular activity in the wall of the fallopian tube. The environment in which the gametes exist a... more
ISBN: 978-91-628-7744-6
URI: http://hdl.handle.net/2077/21415
Appears in Collections:Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses from Sahlgrenska Academy

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