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Now showing items 11-20 of 162
Genomic mutational heterogeneity in cancer. lmproved models and tools for driver gene detection
(2022-01-19)
Cancer is a disease that is strongly related to evolution, as mutations that confer a benefit to individual cells face positive selection and eventually lead to tumorigenesis. As such, the search for genes that drive cancer ...
On the role of Natural Killer cell immunogenetics for the outcome of immunotherapy in acute myeloid leukemia
(2022-02-14)
Numerous studies have revealed that natural killer cells have fundamental roles as effector cells in myeloid leukemias. Thus, understanding NK cell-related biomarkers that influence clinical outcome are warranted. This ...
Prerequisites for palliative care provision in intensive care
(2022-02-08)
Palliative care provision is aimed at improving patients’ quality of life when cure no longer possible through healthcare systems, including intensive care. It has been ob-served that ongoing challenges exist concerning ...
Atrial fibrillation in aging; methodological aspects and the relation to dementia and cerebral vascular disease
(2022-01-12)
Emerging evidence suggest an increased risk of dementia in individuals with atrial fibrillation (AF). However, until recently, few studies have investigated the relation between AF and dementia taking both prevalent and ...
The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury
(2022-01-13)
The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common ...
Acquired Epilepsy with a Focus on Stroke: Treatment and Prognosis
(2022-02-23)
The relationship between epilepsy and stroke is complicated. While stroke is a major cause of epilepsy after middle age, there is also evidence that the risk of stroke is increased in persons with epilepsy. The overall aim ...
Blood Vessels, Biomarkers, and Broken Barriers: lnvestigations of the Brain Vasculature in Models of Neonatal Brain lnjuries
(2022-02-10)
Brain injury during the perinatal period can lead to lifelong impairment in cognitive and motor function, or an early death. Term neonatal encephalopathy and preterm germinal matrix haemorrhage are two conditions that can ...
Fysisk (in)aktivitet i kontorsmiljöer
(GÖTEBORGS UNIVERSITET, 2022-10-20)
Denna rapport ger en systematisk översikt av studier som använt objektiva, tekniska mätmetoder för att belysa hur anställda med kontorsarbete fördelar sin arbetstid mellan olika fysiska aktiviteter (sitta, stå och gå) eller ...
Dopaminergic lnterference for Treatment of Schizophrenia and Alcohol Use Disorder - an experimental study in rats
(2022-05-27)
The neurotransmitter dopamine is involved in several different physiological functions as well as pathological conditions. Two conditions that have been suggested to be related to a low dopaminergic tone in the ventral ...
Understanding mental illness and promoting mental health -Experiences of Exhaustion Disorder and Effects of a Person-Centred eHealth Intervention
(2022-05-11)
Health is subjective, involving the whole person, and cannot be determined by others. It is a resource in life, not merely the absence of disease and illness. Common mental disorders (CMDs), including stress-related ...