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Now showing items 11-20 of 149
Price sensitivity and regional variation in health care
(2021-02-12)
Understanding the consequences of current health policy is important in order to design and develop a health care system suitable for future challenges. The purpose of this thesis is to bring evidence on the determinants ...
The roles of osteoclasts and RUNX2 in the progression of prostate cancer bone metastases
(2021-11-23)
Metastasis to the skeleton is the major cause of death from prostate cancer (PC). Patients with metastatic PC are treated with androgen deprivation therapy (ADT) to decrease testosterone levels and thereby inhibit further ...
The role of glycoproteins in glomerular pathophysiology
(2021-09-01)
Chronic kidney disease (CKD) is increasing worldwide and has a prevalence of around 10%. With time patients are at risk of losing their renal function and will need dialysis or transplantation for survival. There are no ...
On osseointegration in response to controlled surface nanotopography
(2021-05-20)
Knowledge about the biological responses provoked by the surface modification of titanium implants on the nanoscale is still in its infancy. Although in vitro studies claim superior effects considering higher adhesion and ...
Effects of an intervention and an organisational implementation for identification and treatment of common mental disorders in primary healthcare
(2021-05-26)
Aim: This thesis aimed to evaluate the effects of one intervention and one organisational implementation for identification and treatment of common mental disorders (CMDs) in the primary healthcare in Region Västra Götaland, ...
Vaccine-induced aluminium allergy and long-lasting subcutaneous itching nodules
(2021-11-09)
Background: Aluminium contact dermatitis is rare even though aluminium is
frequently used in antiperspirants and sunscreens. Sensitisation to aluminium
is mostly a side effect of aluminium-adsorbed vaccines. These can ...
A search for prognostic biomarkers in diffuse large B-cell lymphoma with proteomics and immunohistochemistry
(2021-11-18)
Diffuse large B-cell lymphoma (DLBCL), the most common lymphoma in the Western world, can by gene expression profiling or immunohisto-chemistry (IHC), be divided into two subgroups according to its “cell-of-origin”. The ...
Management of late term pregnancy
(2021-02-17)
Background: The optimal time point to intervene and induce labour in women with a low-risk pregnancy, in order to decrease perinatal adverse outcome, is up for debate. Some advocate for induction of labour (IOL) at 41 ...
On chaperone co-operation in temporal and spatial protein quality control
(2021-03-29)
In order for a protein to be able to function correctly it needs to adopt its proper fold. Because of this, protein quality control (PQC) is vital at every level of cellular function. The central protein in PQC networks ...
Molecular insights into primer removal during mtDNA replication
(2021-03-01)
Mitochondria are vital for cell survival, and the primary producers of ATP, the energy currency used for various metabolic processes. Mitochondria are unique from other cellular compartments ...