Browsing Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet by Subject "Obesity"
Now showing items 1-20 of 26
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A prevention and health promotion programme for persons with overweight in Primary Health Care Patient outcomes and nurses’ experiences in terms of weight, lifestyle, health and risk factors
(2020-11-20)Background: Primary Healthcare (PHC) is often the first point of contact for patients and thus considered the ideal place to address obesity and lifestyle issues. A weight reduction programme was developed to gain a better ... -
Aspects of heart failure development and prevention in women
(2020-04-15)Heart failure (HF) is a severe progressive condition. Women more often are older and suffer from heart failure with preserved ejection fraction (HFpEF), contrasting to men who more often are younger and suffer from heart ... -
Body mass index and mental health in young people - predictors of early heart failure and cardiomyopathy
(2019-11-18)Heart failure among young people is rare, but in contrast to decreasing incidence rates overall, recent studies have found increasing rates among the young over the last decades. Concomitantly, cardiomyopathies, which ... -
Bone Morphogenetic Protein 4 regulates white, beige and brown adipose tissue
(2017-05-10)Obesity and its associated complications, including Type 2 diabetes, are increasing at an epidemic rate globally. Adipose tissue exerts different functions and is central in energy homeostasis, and it consists of white, ... -
Cardiovascular and metabolic control in obese children and adolescents
(2008)Childhood obesity is an emerging risk factor for disease and mortality worldwide. Thecardiovascular consequences and prevention thereof need to be further investigated. Exerciseand weight loss are well examined and effective ... -
Cardiovascular effects of weight loss. Studies of human obesity
(1999)Obesity is an important determinant of cardiovascular disease. Although several cardiovascular risk factors may improve following weight loss the effects of weight reduction on the heart and vascular system are unclear. ... -
Cardiovascular structure and function in obesity. The impact of body composition, sleep apnea and sustained weight loss
(2012-10-23)Background: Obesity is associated with disturbances in cardiovascular structure and function varying along with the degree of fatness, but the mechanisms underlying this co-variation are unclear. Short-term weight loss ... -
Computed Tomography and Magnetic Resonance Imaging in Determination of Human Body Composition. Methodological and Applied Studies
(2009-02-06)Background: Computed tomography (CT) and magnetic resonance imaging (MRI) provide important research opportunities due to their unique capability of characterizing and quantifying tissues and organs. Ionizing radiation is ... -
Different aspects of psoriasis etiology and treatment
(2012-05-14)Psoriasis is a chronic disease where treatments are often needed throughout life. The quality of life of patients is often affected and comorbidities are common. The overall aim of this thesis was to study treatment regimes, ... -
Effects of surgically induced weight loss on cardiovascular risk factors. Results from the intervention study Swedish Obese Subjects
(2000)Aims: To investigate the effects of large maintained weight losses on body composition, adipose tissue distribution and cardiovascular risk factors, i.e. systolic blood pressure, diastolic blood pressure, glucose, insulin, ... -
Energy intake in the obese - is it possible to obtain unbiased information?
(1998)The primary aim of this thesis was to develop a valid and reproducible dietary questionnaire for large surveys with specific attention to capturing dietary intake in obese subjects. Additional aims were to compare dietary ... -
Genetic epidemiological aspects of obesity and related traits. Human studies in Swedish and North-American cohorts
(2006)Aims: To investigate two obesity candidate genes, the melanocortin-4 receptor (MC4R) and the adiponectin hormone (APM1), by screening their genomic sequences. To search the human genome for quantitative trait loci (QTLs) ... -
Human obesity. Studies of treatment, leptin and the metabolic syndrome
(1999)Aims: To evaluate very low calorie diets (VLCD) in obesity treatment and elucidate leptin's role in the response to severe caloric restriction. To analyse relations between metabolic variables, body composition and liver ... -
Insulin-like Growth Factor-I (IGF-I) and Interleukin-6 (IL-6) regulate body fat
(2002)The aim of this thesis was to investigate the role of insulin-like growth factor-I (IGF-I) and interleukin-6 (IL-6) in the regulation of metabolism and body fat mass. Circulating IGF-I is mainly liver derived, while a large ... -
Investigating the role of Class-1 Phosphoinositide 3 Kinases (PI3Ks) in insulin signaling and obesity
(2020-04-28)Obesity and obesity related diseases such as type 2 diabetes, cardiovascular disorders, and different types of cancer are leading causes of mortality and morbidity in modern society. However, the mechanism that links obesity ... -
Obesity - surgical treatment and molecular mechanisms
(2015-11-11)Obesity is a condition of high prevalence and is associated with increased morbidity and mortality. Bariatric surgery is an effective treatment of obesity and reduces the risk for morbidity and mortality, but little is ... -
Obesity and Common Surgical Disorders, Effects on Incidence and Complications
(2011-04-14)Background: Overweight and obesity are becoming increasingly common, not only in the developed countries but also in developing countries. It is well documented that obesity increases the risk of several medical disorders; ... -
On the effects of obesity treatment
(2021-05-12)Aim: In this thesis the effects of bariatric surgery in individuals with type 1 diabetes (T1D) will be assessed as well as the effects of surgery on risk for heart failure (HF) and atrial fibrillation (AF) in individuals ... -
Pathogenesis of Obesity and Effects of Treatment. Clinical and Molecular Studies on Body Fat, Energy Balance, and Weight Loss.
(2009-06-29)Obesity is common and related to many health problems including various forms of cancer. The condition arises from the imbalance between food intake and energy expenditure, and is strongly influenced by genetic factors. ...