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Pediatric Autoinflammatory Diseases: Conceptual, Clinical, and Mechanistic Dimensions
(2015-09-10)
This thesis focuses on three paediatric autoinflammatory diseases in Sweden today; familial Mediterranean fever (FMF), periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) and synovitis, acne, ...
Progression and treatment of experimental peri-implantitis
(2011-04-21)
Peri-implantitis is characterized by inflammatory lesions in peri-implant tissues and loss of supporting bone. The aims of the present series of studies were to analyze (i) spontaneous progression and (ii) the effect of ...
Inflammation and neuroprotective strategies in the immature brain after hypoxic-ischemic brain injury
(2008-05-13)
Perinatal brain injury, as a result of hypoxia-ischemia (HI) or infection/HI, is a major cause of acute mortality and neurological morbidity in infants and children. The mechanisms of perinatal HI are not fully understood, ...
Molecular and structural patterns of guided bone regeneration (GBR). Experimental studies on the role of GBR membrane and bone substitute materials
(2015-09-15)
The mechanisms of guided bone regeneration (GBR) and bone healing with calcium phosphate (CaP) bone substitutes are not fully understood. The major aim of this thesis was to determine the relationship between the bone ...
Secretory and anti-inflammatory actions of some gastro-intestinal hormones in salivary glands
(2009-09-17)
Textbooks generally state that the secretory activity of salivary glands is solely regulated by nerves. This view is challenged in the present Thesis, using the parotid gland of the anaesthetized rat as experimental in ...
On the importance of inflammation for personality traits and psychiatric morbidity
(2010-12-10)
Background: Pro-inflammatory mediators have been implicated in processes that could be both beneficial and toxic to cells in the brain. On the one hand balanced levels of these mediators favour e.g. neurodevelopmental ...
Regional differences in the response of neural stem cells and their microenvironment to ionizing radiation
(2009-05-14)
Radiation therapy is one of the most effective tools for treating malignant tumors; however, cranial irradiation often results in intellectual impairment and cognitive deficits, such as impaired learning and memory. Ionizing ...
Iron deficiency in female adolescent athletes - prevalence, mechanisms and diagnostics
(2014-05-26)
Background: Iron deficiency (ID) is a very common condition and the most
common nutritional deficiency in the world. ID mostly affects females, both
athletes and non-athletes. Several underlying mechanisms are identified ...
Chronic stress and intestinal barrier function: Implications for infection and inflammation in intensive salmon aquaculture
(2009-10-09)
Aquaculture is a fast growing food-producing sector worldwide. This has increased the awareness among the public as well as governments of the need to secure the welfare and health of farmed fish. Atlantic salmon is, in ...
Pathophysiology of intrauterine asphyxia
(2005)
Background: The premature infant is at increased risk of cerebral white matter damage, oftenreferred to as periventricular leucomalacia, PVL, which is associated with later developmentof cerebral palsy and cognitive ...