Suicidality and depression in older adults: Prevalence, predictors, and outcomes
Abstract
Older adults have the highest risk of suicide of all age groups. Depression is a major risk factor for suicide in late life, but is also associated with lower quality of life, somatic disorders, and premature death. The aim of the thesis was to deepen the understanding of suicidality and depression in the oldest segment of the population.
In Paper I we showed that there was a substantial decrease in suicidal ideation in 85-year-olds between 1986 and 2008, but no change between 2008 and 2015. Suicidal ideation in these cohorts was associated with depressive symptoms, feelings of loneliness and residing in a long-term care facility. In Paper II we found that there was a decrease in depression in 85-year-olds, from 1986 to 2008, and further (in minor but not major depression) from 2008 to 2015. Changes in known risk factors for depression did not explain the decrease. Proportions using antidepressant medication more than doubled from 1986 to 2008 but remained stable from 2008 to 2015. In Paper III we found that a wish to die was associated with all-cause mortality more strongly than both life-weariness and active suicidal ideation. The association remained after adjusting for both somatic and mental disorders and psychosocial factors. In Paper IV we mapped healthcare contacts of older adults (75+) who self-harmed. During the year before self-harm, most contacts were in primary care. There was a sharp increase in contacts with specialized care, and an increase in antidepressant prescriptions, in the months after self-harm. Psychotherapy was rare both before and after self-harm.
The conclusion of this thesis is that there has been a positive development for the oldest age group in Sweden during the past decades regarding depression and suicidality. However, there are still areas with potential for improvement.
Parts of work
I. Jonson M, Sigström R, Mellqvist Fässberg M, Wetterberg H, Rydén L, Rydberg Sterner T, Hedna K, Lagerlöf Nilsson U, Skoog I, Waern, M. Passive and active suicidal ideation in Swedish 85-year-olds: Time trends 1986-2015. Journal of affective disorders. 2021; 290: 300-307. https://www.doi.org/10.1016/j.jad.2021.04.060 II. Jonson M, Sigström R, Hedna K, Rydberg Sterner T, Falk Erhag H, Wetterberg H, Mellqvist Fässberg M, Waern M, Skoog I. Time trends in depression prevalence among Swedish 85-year-olds: repeated cross-sectional population-based studies in 1986, 2008, and 2015. Psychological medicine. 2021; 53(6):1-10. https://www.doi.org/10.1017/S0033291721004335 III. Jonson M, Sigström R, Van Orden KA, Mellqvist Fässberg M, Skoog I, Waern M. Life-Weariness, Wish to Die, Active Suicidal Ideation, and All-Cause Mortality in Population-Based Samples of Older Adults. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2023;31(4):267-276. https://www.doi.org/10.1016/j.jagp.2022.10.003 IV. Hedna K, Jonson M, Sigström R, Åberg M, Wilhelmson K, Waern M. Healthcare visits for mental disorders and use of psychotropic medications before and after self-harm in a cohort aged 75. Aging & mental health. 2023: 1-9. https://www.doi.org/10.1080/13607863.2023.2179974
Degree
Doctor of Philosophy (Medicine)
University
University of Gothenburg. Sahlgrenska Academy
Institution
Institute of Neuroscience and Physiology. Department of Psychiatry and Neurochemistry
Disputation
Fredagen den 29 september, kl. 13.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3, Göteborg.
https://gu-se.zoom.us/j/64085627387?pwd=MnBYQmk1T00zNlNCRlpsRkptLzR1dz09
Date of defence
2023-09-29
mattias.jonson@vgregion.se
Date
2023-09-08Author
Jonson, Mattias
Keywords
Psychiatry
Epidemiology
Suicidology
Gerontology
Publication type
Doctoral thesis
ISBN
978-91-8069-365-3 (PRINT)
978-91-8069-366-0 (PDF)
Language
eng