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Genetics and functions of innate-like lymphocyte subsets

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Title: Genetics and functions of innate-like lymphocyte subsets
Authors: Rolf, Julia
Issue Date: 21-Sep-2007
University: Göteborg University. Sahlgrenska Academy
Institution: Inst of Biomedicine. Dept of Medical Microbiology and Immunology
Parts of work: I. Julia Rolf, Vinicius Motta, Nadia Duarte, Marie Lundholm, Emma Berntman, Marie-Louise Bergman, Lydia Sorokin, Susanna L. Cardell and Dan Holmberg. (2005). The enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11. J Immunol. 174, 4821-7.

II. Julia Rolf, Emma Berntman, Martin Stenström, Emma Smith, Robert Månsson, Hanna Stenstad, Tetsuya Yamagata, William Agace, Mikael Sigvardsson and Susanna L. Cardell. (2007). Molecular profiling reveals distinct functional attributes of CD1d-restricted natural killer (NK) T cell subsets. Submitted manuscript.

III. Emma Berntman, Julia Rolf, Cecilia Johansson, Per Andersson and Susanna L. Cardell. (2005). The role of CD1d-restricted NK T lymphocytes in the immune response to oral infection with Salmonella typhimurium. Eur J Immunol. 35, 2100-9.

Disputation: 9.00 Friday October 12th 2007, Karl Isaksson Medicinaregatan 16
Degree: Doctor of Philosophy (Medicine)
Publication type: Doctoral thesis
Keywords: innate-like lymphocyte
genetic mapping
Salmonella infection
Abstract: The immune system contains three different branches: innate immunity, adaptive immunity and innate-like lymphocytes that share properties both with the innate and adaptive immune cells. The innate-like lymphocytes have the capacity to rapidly become activated by invading pathogens and also to modulate immune responses and thereby inhibit or promote inflammation. However, understanding of the innate-like lymphocyte properties and functions has remained incomplete. This thesis describes the proper... more
ISBN: 978-91-628-7269-4
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses / Doktorsavhandlingar Institutionen för biomedicin
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet



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