Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi by Subject "schizophrenia"
Now showing items 1-9 of 9
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Asperger syndrome and schizophrenia: Psychiatric and social cognitive aspects
(2012-01-23)Background: Asperger syndrome (AS) and schizophrenia are psychiatric disorders often implying low global social functioning and a life-long course. Both disorders are of neurodevelopmental origin and genetic factors are ... -
Cognition and social behaviour in schizophrenia: An animal model investigating the potential role of nitric oxide
(2007-11-27)Cognitive deficits are the single strongest predictor of functional outcome in patients with schizophrenia. Furthermore, these deficits are not satisfactorily alleviated by available antipsychotic treatment. Functional ... -
Cognition, Adherence and Stigma in Schizophrenia. The COAST study
(2015-01-26)Schizophrenia is a serious stigmatizing illness. Antipsychotic medication is a cornerstone in treatment. Non-adherence is a predictor of poor outcome leading to relapse, poor functioning, high mortality and costs. Reported ... -
Cognitive dysfunction studied in animal models of schizophrenia
(2006-12-01)Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental ... -
Dopaminergic lnterference for Treatment of Schizophrenia and Alcohol Use Disorder - an experimental study in rats
(2022-05-27)The neurotransmitter dopamine is involved in several different physiological functions as well as pathological conditions. Two conditions that have been suggested to be related to a low dopaminergic tone in the ventral ... -
Dopaminergic stabilizers for the treatment of schizophrenia. Rat studies focusing on negative symptoms and mechanisms of action
(2007-11-21)Schizophrenia is a severe mental disorder manifested by positive, negative and cognitive symptoms. Current antipsychotic drugs have poor effects on negative and cognitive symptoms, thus necessitating the development of new ... -
On the importance of inflammation for personality traits and psychiatric morbidity
(2010-12-10)Background: Pro-inflammatory mediators have been implicated in processes that could be both beneficial and toxic to cells in the brain. On the one hand balanced levels of these mediators favour e.g. neurodevelopmental ... -
On the influence of dopamine-related genetic variation on dopamine-related disorders
(2009-11-13)Rationale: Dopamine synthesizing neurons are involved in a wide variety of functions. The most prominent dopamine pathways originate in the midbrain. The development, function and survival of these dopaminergic neurons are ... -
The prefrontal cortex and information processing : nitric oxide signaling studied in an animal model of schizophrenia
(2008-11-28)The prefrontal cortex has been extensively linked to several cognitive domains that are severely compromised in schizophrenia. It has therefore become a key region for studies on the disabling cognitive dysfunction commonly ...