Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för kemi by Subject "Metabolism"
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Electrochemical and Enzymatic In Vitro Studies on Reactive Drug Metabolites Synthesis, Characterization and Avoidance
(2010-05-03)ABSTRACT During development of pharmaceuticals, it is essential to as early as possible identify and preferably avoid formation of reactive metabolites and ... -
Isothiocynates as skin sensitizers. Bioactivation and distribution in skin and lymph nodes
(2010-11-05)Development of contact dermatitis can be caused by electrophilic compounds (haptens) or prohaptens that come into contact with the skin. A prohapten is a compound seemingly harmless at first sight that can be transformed ...