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Blood Pressure Elevation - Impact on Cardiovascular Structure and Endogenous Fibrinolysis
(2008-05-16)
Blood pressure elevation is a major risk factor for cardiovascular events and the risk increases in a dose-dependant manner. It is of importance to identify subjects prone to develop hypertension and adverse cardiovascular ...
Pharmacological stimulation of endothelial function and long-term impact of hypertension in man
(2016-05-06)
Background: Ischemic heart disease is a major cause of death globally. Rupture of a coronary atherosclerotic
plaque with occluding thrombus formation is the main cause of myocardial ischemia and infarction.
A healthy ...
Impairment of Endothelial Thromboprotective Function by Haemodynamic and Inflammatory Stress - Implications for hypertensive disease
(2007-06-29)
The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (t-PA). The endothelium synthesizes and stores t-PA and regulated release of the enzyme is an important local ...