Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Subject "negative selection"
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Thymic exosomes - effects on selection and maturation of thymocytes
(2022-04-22)T cell tolerance is primarily shaped in the thymus, through direct and indirect presentation of self-antigens to developing T cells. Medullary thymic epithelial cells (mTECs), producing and expressing self-antigens, together ...