Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för biomedicin by Subject "targeted therapy"
Now showing items 1-3 of 3
-
Profiling of Small Intestine Neuroendocrine Tumors
(2014-11-04)Small intestine neuroendocrine tumors (SI-NETs) are malignant neoplasms usually presenting with disseminated disease and symptoms of hormone overproduction. Radical surgery is curative but can only be performed for localized ... -
The impact of the progranulin-sortilin axis on breast cancer stem cell activity and patient outcome
(2021-08-18)Breast cancer is the most common cancer in women worldwide. Still today, despite current breast cancer therapies, many patients experience treatment resistance and relapse, which are believed to be due to failure in targeting ... -
Transcriptomic and functional studies of fusion oncogene-driven salivary gland tumors
(2020-11-25)Fusion genes are potent oncogenic drivers resulting from exchange of regulatory/coding sequences between two genes. They were originally identified in leukemias but are now recognized as key oncogenic events also in many ...