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Recurrent Aphthous Stomatitis - A study, with emphasis on host genetics, oral microbiota composition, and immunoregulatory networks


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Title: Recurrent Aphthous Stomatitis - A study, with emphasis on host genetics, oral microbiota composition, and immunoregulatory networks
Authors: Bankvall, Maria
E-mail: maria.bankvall@odontologi.gu.se
Issue Date: 17-Jan-2017
University: University of Gothenburg. Sahlgrenska Academy
Institution: Institute of Odontology. Department of Oral Medicine and Pathology
Parts of work: I. Bankvall M, Östman S, Jontell M, Torinsson-Naluai Å. A genome-wide association study of recurrent aphthous stomatitis. In manuscript.

II. Bankvall M, Sjöberg F, Gale G, Wold A, Jontell M, Östman S. The oral microbiota of patients with recurrent aphthous stomatitis. J Oral Microbiol. 2014 Oct 29;6:25739.
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III. Bankvall M, Jontell M, Wold A, Östman S. Tissue-specific differences in immune cell subsets located in the oral-associated lymphoid tissues. In manuscript.

IV. Bankvall M, Östberg AK, Jontell M, Wold A, Östman S. The engagement of oral-associated lymphoid tissues during oral versus gastric antigen administration. Immunology. 2016 Sep;149(1):98-110.
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Date of Defence: 2017-02-03
Disputation: Fredagen den 3 februari 2017, kl.9.00, Hörsal Arvid Carlsson, Academicum, Medicinaregatan 3, Göteborg
Degree: Doctor of Philosophy (Odontology)
Publication type: Doctoral thesis
Keywords: Aphthous stomatitis
Oral mucosa
Oral medicine
Genome-wide association study
Genetic linkage
Association
Genetic polymorphism
Microbiota
Restriction fragment length polymorphism
Antigen-presenting cell
T-lymphocyte
Lymph node
Flow cytometry
Abstract: Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal lesions. The aetiology is unknown and currently there is no consensus regarding suitable treatment regimens. RAS is recognised as a multi-factorial condition in which both endogenous and exogenous factors contribute to the recurrent oral ulcerations characteristic of this oral mucosal disease. The overall aim of this thesis was to study the aetiological factors associated with RAS. Previously, it has been suggested that ... more
ISBN: 978-91-628-9993-6 (PDF)
978-91-628-9994-3 (Print)
URI: http://hdl.handle.net/2077/48668
Appears in Collections:Doctoral Theses from Sahlgrenska Academy
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Doctoral Theses / Doktorsavhandlingar Institutionen för odontologi

 

 

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