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Regulation of innate and adaptive immune responses by Gram-positive and Gram-negative bacteria
(2009-05-20)
Bacteria are classified as Gram-positive or Gram-negative, depending on their cell wall structure. The role of the bacterial cell wall in immune regulation is the focus of the current work.
Most Gram-positive bacteria ...
Mechanisms of dendritic cell maturation induced by intracellular bacteria infection
(2007-10-02)
Dendritic cells (DCs) are essential for the development of an immune response against pathogens such as Listeria monocytogenes and Salmonella typhimurium. This is mostly because of their unique capacity to stimulate naïve ...
Oxidant-induced cell death in lymphocytes: mechanisms of induction and resistance
(2007-04-16)
Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pivotal roles in immunity. Patients lacking a functional NADPH oxidase suffer from chronic granulomatous disease, which is ...