GUPEA >
Faculty of Science / Naturvetenskapliga fakulteten >
Department of Physics / Institutionen för fysik >
Doctoral Theses / Doktorsavhandlingar Institutionen för fysik >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/2077/21548
|
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
gupea_2077_21548_1.pdf | Abstract | 151Kb | Adobe PDF | ![]() View/Open |
gupea_2077_21548_2.pdf | Thesis | 1060Kb | Adobe PDF | ![]() View/Open |
Title: | Quantitative analysis of tumor growth and response to therapy |
Authors: | Mehrara, Esmaeil |
E-mail: | e.mehrara@radfys.gu.se e.mehrara@gmail.com |
Issue Date: | 14-Jan-2010 |
University: | Göteborgs universitet. Naturvetenskapliga fakulteten |
Institution: | Department of Physics ; Institutionen för fysik |
Parts of work: | Mehrara E, Forssell-Aronsson E, Ahlman H, Bernhardt P. Specific growth rate versus doubling time for quantitative characterization of tumor growth rate. Cancer Research; 67(8): 3970-3975, 2007, VIEW ARTICLE Mehrara E, Forssell-Aronsson E, Ahlman H, Bernhardt P. Quantitative analysis of tumor growth rate and changes in tumor marker level: Specific growth rate versus doubling time. Acta Oncologica; 48: 591-597, 2009, VIEW ARTICLE Mehrara E, Forssell-Aronsson E, Johansson V, Kölby L, Ahlman H, Bernhardt P. Analysis of the growth model of solid tumors in clinical studies. Manuscript, 2010 Mehrara E, Forssell-Aronsson E, Bernhardt P. Objective assessment of solid tumor response to therapy based on tumor growth kinetics. Manuscript, 2010 |
Date of Defence: | 2010-02-05 |
Disputation: | Fredagen den 5 Februari 2010, kl. 9.15, Konferenscentrum Wallenberg, sal Lyktan, Medicinaregatan 20A |
Degree: | Doctor of Philosophy |
Publication type: | Doctoral thesis |
Keywords: | tumor growth response therapy modeling clinical |
Abstract: | Modeling the natural growth of tumors is of value for evaluation of tumor progression and optimization of treatment strategies. However, modeling tumor growth based on clinical data is hampered by the limited data available, since therapy is in general initiated as early as possible after diagnosis. Most descriptions of tumor growth rate are thus based on two data points per tumor, and assuming exponential tumor growth. The time needed for a tumor to double in volume, doubling time (DT), is wide... more |
ISBN: | 978-91-628-7997-6 |
URI: | http://hdl.handle.net/2077/21548 |
Appears in Collections: | Doctoral Theses / Doktorsavhandlingar Institutionen för fysik Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet |