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Quantitative analysis of tumor growth and response to therapy


Please use this identifier to cite or link to this item: http://hdl.handle.net/2077/21548

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Title: Quantitative analysis of tumor growth and response to therapy
Authors: Mehrara, Esmaeil
E-mail: e.mehrara@radfys.gu.se
e.mehrara@gmail.com
Issue Date: 14-Jan-2010
University: Göteborgs universitet. Naturvetenskapliga fakulteten
Institution: Department of Physics ; Institutionen för fysik
Parts of work: Mehrara E, Forssell-Aronsson E, Ahlman H, Bernhardt P. Specific growth rate versus doubling time for quantitative characterization of tumor growth rate. Cancer Research; 67(8): 3970-3975, 2007,
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Mehrara E, Forssell-Aronsson E, Ahlman H, Bernhardt P. Quantitative analysis of tumor growth rate and changes in tumor marker level: Specific growth rate versus doubling time. Acta Oncologica; 48: 591-597, 2009,
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Mehrara E, Forssell-Aronsson E, Johansson V, Kölby L, Ahlman H, Bernhardt P. Analysis of the growth model of solid tumors in clinical studies. Manuscript, 2010

Mehrara E, Forssell-Aronsson E, Bernhardt P. Objective assessment of solid tumor response to therapy based on tumor growth kinetics. Manuscript, 2010
Date of Defence: 2010-02-05
Disputation: Fredagen den 5 Februari 2010, kl. 9.15, Konferenscentrum Wallenberg, sal Lyktan, Medicinaregatan 20A
Degree: Doctor of Philosophy
Publication type: Doctoral thesis
Keywords: tumor
growth
response
therapy
modeling
clinical
Abstract: Modeling the natural growth of tumors is of value for evaluation of tumor progression and optimization of treatment strategies. However, modeling tumor growth based on clinical data is hampered by the limited data available, since therapy is in general initiated as early as possible after diagnosis. Most descriptions of tumor growth rate are thus based on two data points per tumor, and assuming exponential tumor growth. The time needed for a tumor to double in volume, doubling time (DT), is wide... more
ISBN: 978-91-628-7997-6
URI: http://hdl.handle.net/2077/21548
Appears in Collections:Doctoral Theses / Doktorsavhandlingar Institutionen för fysik
Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet

 

 

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