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NEURAL STEM/PROGENITOR CELLS IN THE POST-ISCHEMIC ENVIRONMENT: Proliferation, Differentiation and Neuroprotection
(2007-06-04)
Stroke is one of the leading causes of chronic disability and death in the Western world. Today, no treatment can repair the cellular loss associated with an ischemic lesion. However, the discovery and dynamic regulation ...
Studies on pathophysiological mechanisms in experimental models of acute renal failure
(2007-02-19)
Acute renal failure (ARF) affects 5-20 % of critically ill patients and is an independent risk factor for death in this patient population. Reactive oxygen species, thrombin and endothelin-1 (ET-1) are increased in ARF, ...
Improved bioenergetic recovery during experimental ischemia and reperfusion by irradiation
(2007-11-16)
Prolonged ischemia and reperfusion frequently occur during clinical operations. The bioenergetic status decreases during ischemia and reactive oxygen species (ROS) are formed during reperfusion, which may lead to irreversible ...