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Now showing items 81-90 of 149
Interaction of genetic susceptibility and traffic-related air pollution in cardiovascular disease
(2015-01-28)
This thesis aimed at investigating gene-environment interaction in cardiovascular disease (CVD). A study population of 618 coronary heart disease (CHD) cases (of which 192 first-time acute myocardial infarction (AMI) ...
Navigating towards a self-determined daily life in old age. Experiences, instrument evaluation and explanatory factors.
(2015-05-18)
Aim: The overall aim of this thesis was to explore self-determination in the context of community-dwelling older persons with different degrees of dependence in daily activities. Methods: Using a qualitative, grounded ...
Susceptibility to chronic liver disease
(2015-03-06)
The onset and the progression of chronic liver disease involve environmental and genetic
factors. Hepatic stellate cells (HSCs) are important players in these processes and are the
main storage site for retinol. We studied ...
Predictors of Complications after Anterior Cruciate Ligament Injury
(2015-04-10)
BACKGROUND: An anterior cruciate ligament (ACL) tear is a serious knee injury that frequently affects young individuals active in soccer, alpine skiing, handball and basketball. Regardless of treatment, an ACL injury is ...
Small-Scale Absorbed Dose Modelling in Selective Internal Radiation Therapy
(2015-04-30)
Radioembolisation (RE), with yttrium-90 (90Y) labelled microspheres, is an increasingly common treatment method for unresectable liver tumours. The tolerable mean absorbed dose for normal liver (NL) tissue is higher in RE ...
Anterior cruciate ligament reconstruction: long-term outcome in adults and adolescents. Clinical results, health-related quality of life, radiographic findings and boone mineral assessments
(2015-09-10)
The aim of this thesis was to measure health-related quality of life (HRQoL) and assess pre-operative factors predicting good outcome of HRQoL after anterior cruciate ligament (ACL) reconstruction. Furthermore, to specifically ...
Studies on glycosphingolipids in infection, immunity and differentiation
(2015-04-17)
Cell surface glycoconjugates play a role in many biological processes such as responses to microbial infections, cell-cell interactions, differentiation, and inflammatory responses. The present work is focused on structural ...
On cerebrospinal fluid biomarkers of HIV-1 infection
(2015-11-26)
HIV invades the central nervous system (CNS) shortly after transmission and is present throughout the course of infection, causing immune activation and neuroinflammation. If left untreated, more than 20% of patients with ...
Effectiveness of implant therapy in Sweden
(2015-09-10)
Dental implants are commonly used in restorative therapy in patients with partial
or full edentulism. Knowledge regarding the outcome of this kind of treatment has
been limited to evaluations of efficacy, i.e. therapy ...
Immune regulation by selective estrogen receptor modulators
(2015-04-30)
At menopause, the levels of estrogen decline, leading to loss of estrogen-mediated protective effects on bone and an increased risk of osteoporosis. Hormone replacement therapy, containing estrogen, has been used for many ...