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Pathophysiological impact of targeting the ROS-p53 axis
(2014-10-21)
The goal of this PhD thesis was to define the importance of the interplay between reactive oxygen species (ROS) and their activation of the tumor suppressor p53 in development and disease. We addressed this question using ...
Elevated calcium concentration, is it dangerous? Long-term follow-up in primary care
(2014-02-12)
Background and aims: Patients with hypercalcaemia are relatively common in primary care; the most frequent causes are primary hyperparathyroidism (pHPT) and cancer. Many patients with pHPT have such discrete symptoms that ...