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Human embryonic stem cells for bone engineering applications
(2011-05-26)
The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and ...
Mechanisms of Osseointegration: Experimental Studies on Early Cellular and Molecular Events in vivo
(2010-06-14)
The early cellular and molecular activities determining the early tissue response and bone formation at bone/implant interface are not fully understood. The general aim of the current thesis was to develop a model for ...
On cobalt-chrome frameworks in implant dentistry
(2009-11-22)
Background: Cobalt-chrome (CoCr) alloys have been used in dentistry in decades but very
little is known about their behavior and biological impact as framework materials in implant
dentistry. Furthermore, few studies ...
Infections associated with percutaneous osseointegrated titanium implants for limb prostheses
(2017-10-26)
Femoral amputation is a devastating event. Percutaneous, bone anchored
prosthetic systems reduce problems associated with socket suspended
prostheses, but the design is inherently vulnerable to infection. The aims of
this ...
Progression and treatment of experimental peri-implantitis
(2011-04-21)
Peri-implantitis is characterized by inflammatory lesions in peri-implant tissues and loss of supporting bone. The aims of the present series of studies were to analyze (i) spontaneous progression and (ii) the effect of ...
On the influence of micro-and macroscopic surface modifications on bone integration of titanium implants
(2007-01-31)
Background: Osseointegrated titanium implants are routinely used in clinical denstistry
as anchorage units for dental prostheses. Although the overall clinical results are good,
there are clinical situations when an ...
Soft tissue integration to dental implants
(2008-09-26)
Soft tissue integration is a prerequisite for implant success. The role of the soft tissue barrier at implants is to provide an effective seal that protects the underlying bone and prevents access for microorganisms and ...
Methods for evaluation of early bone healing at titanium implants
(2008-10-03)
Titanium has for a long time been the implant material of choice when in need for abilities as
strength, biocompatibility and stability. Although numbers of studies have been made, little is
known about the early events ...
On a novel technique for preparation and analysis of the implant surface and its interface to bone
(2008-06-13)
The ultrastructural and biomechanical properties of the bone-implant interface are important factors for implant performance. For further understanding of the osseointegration process novel tools enabling analysis of the ...
Molecular and cellular interactions on noble metal nanopatterned surfaces − applications towards bone, soft tissue and infection control
(2014-05-09)
Biomaterial-associated infection is recognised as one of the main risks for failure of medical devices. The presence of a foreign material in tissues has been suggested to compromise the ability of host cells to eradicate ...